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改善孕期饮食和铁叶酸摄入量的实践试验(TIPs)——印度瓦拉纳西农村孕妇的一项准实验研究

Trials of Improved Practices (TIPs) to Enhance the Dietary and Iron-Folate Intake during Pregnancy- A Quasi Experimental Study among Rural Pregnant Women of Varanasi, India.

作者信息

Shivalli Siddharudha, Srivastava Ratan Kumar, Singh Gyan Prakash

机构信息

Department of Community Medicine, Yenepoya Medical College, Yenepoya University, Mangalore, Karnataka, India.

Department of Community Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

出版信息

PLoS One. 2015 Sep 14;10(9):e0137735. doi: 10.1371/journal.pone.0137735. eCollection 2015.

Abstract

BACKGROUND

Behavior Change Communications (BCC) play a decisive role in modifying socio-cultural norms affecting the perception and nutritional practices during pregnancy.

OBJECTIVE

To examine the effectiveness of 'Trials of Improved Practices' (TIPs) on dietary and iron-folate intake during pregnancy.

DESIGN

Community based quasi experimental study with a control group.

SETTING

Four villages of Chiraigaon Community Development Block of Varanasi, India from May 2010 and recruited from August 2010. End line assessment, after 12 weeks of intervention, was completed in April 2011.

PARTICIPANTS

Pregnant women in 13-28 weeks of gestation.

INTERVENTION

TIPs was implemented in addition to ongoing essential obstetric care services in two villages through 3 home (assessment, negotiation and evaluation) visits and only assessment and evaluation visits in the other two control villages. Interpersonal communication, endorsing the active participation of family members and home based reminder materials were the TIPs based strategies. The effect of TIPs was assessed by comparing key outcome variables at baseline and after 12 weeks of intervention.

OUTCOME MEASURES

Hemoglobin%, anemia prevalence, weight gain, compliance for iron-folate supplementation and dietary intake of calorie, protein, calcium and iron.

RESULTS

A total of 86 participants completed the study. At the end, mean hemoglobin levels were 11.5±1.24 g/dl and 10.37±1.38 g/dl in the TIPs and control groups, respectively. The prevalence of anemia reduced by half in TIPs group and increased by 2.4% in the control group. Weight gain (grams/week) was significantly (p<0.01) higher in TIPs group (326.9±91.8 vs. 244.6±97.4). More than 85% of the PW in TIPs group were compliant for Iron-folate and only 38% were compliant among controls. The mean intake of protein increased by 1.78gm in intervention group and decreased by 1.81 gm in controls (p<0.05). More than two thirds of PW in TIPs group were taking one extra meal and only one third of controls were doing the same.

CONCLUSION

TIPs found to be an effective approach to improve the nutritional status of pregnant women in the study area. TIPs strategy could be further explored on larger sample representing different socio-cultural and geographical areas.

TRIAL REGISTRATION

Clinical Trial Registry of India CTRI/2015/02/005517.

摘要

背景

行为改变沟通(BCC)在改变影响孕期认知和营养行为的社会文化规范方面起着决定性作用。

目的

研究“改进实践试验”(TIPs)对孕期饮食和铁叶酸摄入量的效果。

设计

设有对照组的社区准实验研究。

地点

印度瓦拉纳西市奇莱冈社区发展区的四个村庄,于2010年5月开始选取,并于2010年8月招募。在干预12周后,于2011年4月完成终线评估。

参与者

妊娠13 - 28周的孕妇。

干预措施

在两个村庄,除了提供现有的基本产科护理服务外,还通过3次家访(评估、协商和评价)实施TIPs;在另外两个对照村庄只进行评估和评价家访。基于TIPs的策略包括人际沟通、鼓励家庭成员积极参与以及家庭提醒材料。通过比较基线和干预12周后的关键结局变量来评估TIPs的效果。

结局指标

血红蛋白百分比、贫血患病率、体重增加、铁叶酸补充剂的依从性以及卡路里、蛋白质、钙和铁的饮食摄入量。

结果

共有86名参与者完成了研究。最后,TIPs组和对照组的平均血红蛋白水平分别为11.5±1.24 g/dl和10.37±1.38 g/dl。TIPs组的贫血患病率降低了一半,而对照组增加了2.4%。TIPs组的体重增加(克/周)显著更高(p<0.01)(326.9±91.8对244.6±97.4)。TIPs组超过85%的孕妇依从铁叶酸补充,而对照组中只有38%依从。干预组蛋白质的平均摄入量增加了1.78克,对照组减少了1.81克(p<0.05)。TIPs组超过三分之二的孕妇额外加餐,而对照组只有三分之一这样做。

结论

在研究区域,TIPs被发现是改善孕妇营养状况的有效方法。TIPs策略可在代表不同社会文化和地理区域的更大样本上进一步探索。

试验注册

印度临床试验注册中心CTRI/2015/02/005517

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c9b/4569533/00779e9b1db1/pone.0137735.g001.jpg

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