Kasai Mari, Ichimura Tomoyuki, Murakami Makoto, Matsuda Makiko, Kawamura Naoki, Sumi Toshiyuki
Department of Obstetrics and Gynecology, Osaka City University Graduate School of Medicine, Osaka, Japan.
J Obstet Gynaecol Res. 2015 Oct;41(10):1664-8. doi: 10.1111/jog.12759. Epub 2015 Sep 14.
The incidence of primary malignant lymphoma arising in the female genital tract is extremely rare and constitutes approximately 0.05% of malignant tumors. Uterine malignant lymphoma develops in the endometrial stroma, causing minimal necrosis. It is therefore difficult to diagnose malignant lymphoma, as it does not involve genital bleeding or epithelial defects. We have performed transcervical needle biopsies from deep in the myometrium, with the purpose of diagnosing uterine muscle layer lesions, such as leiomyosarcoma, but this is an unusual method. In this report, we suggest that transcervical needle biopsy is useful in the diagnosis of uterine malignant lymphoma.
原发性女性生殖道恶性淋巴瘤的发病率极低,约占恶性肿瘤的0.05%。子宫恶性淋巴瘤发生于子宫内膜间质,坏死极少。因此,由于不涉及生殖道出血或上皮缺损,恶性淋巴瘤很难诊断。我们曾为诊断子宫肌层病变(如平滑肌肉瘤),从子宫肌层深部进行经宫颈针吸活检,但这是一种不常用的方法。在本报告中,我们认为经宫颈针吸活检对子宫恶性淋巴瘤的诊断有用。