a Morningside Translations , New York , NY , USA.
b Drew University , Madison , NJ , USA.
Crit Rev Biotechnol. 2016 Dec;36(6):1050-1065. doi: 10.3109/07388551.2015.1083943. Epub 2015 Sep 18.
Modern research has focused on the microbial transformation of a huge variety of organic compounds to obtain compounds of therapeutic and/or industrial interest. Microbial transformation is a useful tool for producing new compounds, as a consequence of the variety of reactions for natural products. This article describes the production of many important compounds by biotransformation. Emphasis is placed on reporting the metabolites that may be of special interest to the pharmaceutical and biotechnological industries, as well as the practical aspects of this work in the field of microbial transformations.
现代研究集中于微生物转化大量的有机化合物以获得具有治疗和/或工业价值的化合物。微生物转化是生产新化合物的有用工具,这是由于天然产物的反应种类繁多。本文描述了通过生物转化生产许多重要化合物的方法。重点报告了可能对制药和生物技术行业特别感兴趣的代谢产物,以及微生物转化领域中这项工作的实际方面。