既往抑郁症诊断、绝经状态、血管舒缩症状及神经质对更年期女性抑郁症状的影响：一项30个月的随访研究
Effect of previous diagnoses of depression, menopause status, vasomotor symptoms, and neuroticism on depressive symptoms among climacteric women: A 30-month follow-up.
作者信息
Chou Cheng-Hsiang, Ko Huei-Chen, Wu Jo Yung-Wei, Chang Fong-Ming, Tung Yuk-Ying
机构信息
Institute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Institute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Department of Psychology, College of Humanities and Social Sciences, Asia University, Wufeng, Taichung, Taiwan.
出版信息
Taiwan J Obstet Gynecol. 2015 Aug;54(4):385-9. doi: 10.1016/j.tjog.2015.03.004.
OBJECTIVES
The research was designed to examine the impact of the previous diagnoses of depression, menopause status, vasomotor symptoms, and neuroticism on depressive symptoms among menopausal women in Taiwan over a 30-month follow-up.
MATERIALS AND METHODS
A community-based sample of 190 middle-aged women was enrolled. The Menopausal Symptoms Scale, Neuroticism Extraversion Openness Five Factor Inventory-Chinese version, and Ko's Depression Inventory were applied, and results were assessed. In addition, each woman underwent a semistructured diagnostic interview with the Chinese version of the Modified Schedule of Affective Disorders and Schizophrenia-Lifetime to obtain her lifetime psychiatric history. After 30 months, 111 participants completed follow-up questionnaires.
RESULTS
Results of the hierarchical multiple regression analyses showed that depressive symptoms during the menopause transition predicted depressive symptoms over 30 months. After controlling for depressive symptoms during the menopause transition, the previous diagnoses of depression, menopause status, and vasomotor symptoms could not predict depressive symptoms over 30 months, whereas neuroticism still predicted depressive symptoms over 30 months.
CONCLUSION
The research suggested that neuroticism plays an important role in the persistence of depression among climacteric women after 30 months.
目的
本研究旨在探讨既往抑郁症诊断、绝经状态、血管舒缩症状和神经质对台湾绝经后妇女30个月随访期间抑郁症状的影响。
材料与方法
招募了190名中年女性组成的社区样本。应用绝经症状量表、神经质外向性开放性五因素问卷中文版和柯氏抑郁量表，并对结果进行评估。此外，每位女性都接受了中文版修订版情感障碍和精神分裂症检查表的半结构化诊断访谈，以获取其终生精神病史。30个月后，111名参与者完成了随访问卷。
结果
分层多元回归分析结果显示，绝经过渡期间的抑郁症状可预测30个月后的抑郁症状。在控制了绝经过渡期间的抑郁症状后，既往抑郁症诊断、绝经状态和血管舒缩症状无法预测30个月后的抑郁症状，而神经质仍然可以预测30个月后的抑郁症状。
结论
该研究表明，神经质在更年期女性30个月后抑郁症的持续存在中起重要作用。
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