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分析导致绝经前、围绝经期和绝经后妇女出现抑郁症状的社会人口学、心理和遗传因素。

Analysis of Sociodemographic, Psychological, and Genetic Factors Contributing to Depressive symptoms in Pre-, Peri- and Postmenopausal Women.

机构信息

Department of Nursing, Pomeranian Medical University in Szczecin, ul. Żołnierska 48, 71-210 Szczecin, Poland.

Department of Public Health, Pomeranian Medical University in Szczecin, ul. Żołnierska 48, 71-210 Szczecin, Poland.

出版信息

Int J Environ Res Public Health. 2018 Apr 10;15(4):712. doi: 10.3390/ijerph15040712.

Abstract

UNLABELLED

Depressive symptoms that are faced by women in the pre-, peri-, and postmenopausal periods are determined by a wide array of sociodemographic, psychological, and biological variables. The aim of our study was to identify factors that contribute to depressive problems at this stage of life. The study included 815 healthy Polish women aged 45-60 years. The survey part was conducted using the Beck Depression Inventory (BDI), the State-Trait Anxiety Inventory (STAI), the Neuroticism-Extroversion-Openness Five Factor Inventory (NEO-FFI), and a self-developed questionnaire. Genetic analysis was also performed. Depressive symptoms were observed in 25.5% of participants. 70% of the women were postmenopausal. No statistically significant differences in the severity of depressive symptoms were demonstrated with regard to genetic variables ( > 0.05). Reproductive capacity ( < 0.001), employment ( < 0.001), and being married ( < 0.018) were found to reduce the incidence of depressive symptoms. The contribution of personality and anxiety as a trait to depressive symptoms varied.

CONCLUSIONS

The factors predisposing pre-, peri-, and postmenopausal women to depressive symptoms include lower education, lack of a life partner, unemployment, high anxiety, and neurotic personality. No evidence was found for the contribution of genetic factors to depressive symptoms in the examined women.

摘要

未标注

处于绝经前期、围绝经期和绝经后期的女性所面临的抑郁症状是由广泛的社会人口学、心理和生物学变量决定的。我们的研究旨在确定导致女性在这一人生阶段出现抑郁问题的因素。研究纳入了 815 名年龄在 45-60 岁的健康波兰女性。调查部分采用贝克抑郁量表(BDI)、状态-特质焦虑量表(STAI)、神经质-外向性-开放性五因素量表(NEO-FFI)和一份自拟问卷进行。还进行了基因分析。研究发现,25.5%的参与者存在抑郁症状。70%的女性处于绝经后状态。遗传变量(>0.05)与抑郁症状严重程度无统计学差异。研究发现,生育能力(<0.001)、就业(<0.001)和已婚状况(<0.018)降低了抑郁症状的发生率。个性和焦虑特质对抑郁症状的贡献程度存在差异。

结论

易导致绝经前期、围绝经期和绝经后期女性出现抑郁症状的因素包括教育程度较低、没有生活伴侣、失业、焦虑程度较高和神经质人格。在被研究的女性中,没有证据表明遗传因素对抑郁症状有影响。

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