氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描在内分泌恶性肿瘤靶向放射性核素治疗中的作用
Role of Fluorodeoxyglucose PET/Computed Tomography in Targeted Radionuclide Therapy for Endocrine Malignancies.
作者信息
Pattison David A, Hofman Michael S
机构信息
Centre for Cancer Imaging, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Endocrinology Service, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.
Centre for Cancer Imaging, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
出版信息
PET Clin. 2015 Oct;10(4):461-76. doi: 10.1016/j.cpet.2015.05.005. Epub 2015 Jul 3.
This review provides practical guidance for clinicians involved in the management of endocrine malignancies, including endocrinologists, medical oncologists, surgeons and nuclear medicine specialists regarding the indications and use of 2-fluoro-2-deoxy-d-glucose F-18 (FDG) PET/computed tomography (CT), particularly with respect to targeted radionuclide therapy. Key principles of FDG PET/CT for radionuclide therapy are explored in detail using gastroenteropancreatic neuroendocrine tumors as a prototype endocrine malignancy. The relevant literature is reviewed, and practical application in this new and emerging field is highlighted with the use of case examples.
本综述为参与内分泌恶性肿瘤管理的临床医生提供实用指导，这些医生包括内分泌科医生、医学肿瘤学家、外科医生和核医学专家，内容涉及2-氟-2-脱氧-D-葡萄糖F-18（FDG）PET/计算机断层扫描（CT）的适应证和应用，特别是在靶向放射性核素治疗方面。以胃肠胰神经内分泌肿瘤作为内分泌恶性肿瘤的典型例子，详细探讨了用于放射性核素治疗的FDG PET/CT的关键原则。对相关文献进行了综述，并通过案例展示突出了这一新兴领域的实际应用。
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