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氟代脱氧葡萄糖正电子发射断层显像/计算机断层扫描(FDG-PET/CT)在现代医学中的关键作用。

The pivotal role of FDG-PET/CT in modern medicine.

作者信息

Hess Søren, Blomberg Björn A, Zhu Hongyun June, Høilund-Carlsen Poul Flemming, Alavi Abass

机构信息

Department of Nuclear Medicine, Odense University Hospital, Soender Boulevard 29, 5000 Odense, Denmark.

Department of Nuclear Medicine, Odense University Hospital, Soender Boulevard 29, 5000 Odense, Denmark; Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.

出版信息

Acad Radiol. 2014 Feb;21(2):232-49. doi: 10.1016/j.acra.2013.11.002.

Abstract

The technology behind positron emission tomography (PET) and the most widely used tracer, 2-deoxy-2-[18F]fluoro-D-glucose (FDG), were both conceived in the 1970s, but the latest decade has witnessed a rapid emergence of FDG-PET as an effective imaging technique. This is not least due to the emergence of hybrid scanners combining PET with computed tomography (PET/CT). Molecular imaging has enormous potential for advancing biological research and patient care, and FDG-PET/CT is currently the most widely used technology in this domain. In this review, we discuss contemporary applications of FDG-PET and FDG-PET/CT as well as novel developments in quantification and potential future indications including the emerging new modality PET/magnetic resonance imaging.

摘要

正电子发射断层扫描(PET)技术以及最广泛使用的示踪剂2-脱氧-2-[¹⁸F]氟-D-葡萄糖(FDG)均诞生于20世纪70年代,但在最近十年中,FDG-PET迅速成为一种有效的成像技术。这尤其得益于将PET与计算机断层扫描相结合的混合扫描仪(PET/CT)的出现。分子成像在推动生物学研究和患者护理方面具有巨大潜力,而FDG-PET/CT是目前该领域应用最广泛的技术。在本综述中,我们讨论了FDG-PET和FDG-PET/CT的当代应用,以及在定量方面的新进展和潜在的未来适应症,包括新兴的新模式PET/磁共振成像。

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