Department of Biochemistry and Molecular Biology, Graduate School and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.
Mol Cell. 2015 Sep 17;59(6):887-9. doi: 10.1016/j.molcel.2015.09.004.
In this issue of Molecular Cell, Liu et al. (2015) report that fission yeast Nbr1, sharing a partial homology to the mammalian macroautophagy receptor NBR1, acts as a receptor for ESCRT-dependent endosomal microautophagy that delivers two hydrolytic enzymes from the cytosol to the vacuole.
在本期《分子细胞》中,刘等人(2015 年)报道称,裂殖酵母 Nbr1 与哺乳动物巨自噬受体 NBR1 具有部分同源性,作为 ESCRT 依赖性内体微自噬的受体发挥作用,将两种来自细胞质的水解酶递送到液泡中。