性与生殖健康的多用途预防技术:绘制全球对引入新型预防产品的需求情况。

Multipurpose prevention technologies for sexual and reproductive health: mapping global needs for introduction of new preventive products.

作者信息

Schelar Erin, Polis Chelsea B, Essam Timothy, Looker Katharine J, Bruni Laia, Chrisman Cara J, Manning Judy

机构信息

Office of Population and Reproductive Health, United States Agency for International Development, CP3-11090A, 1300 Pennsylvania Avenue NW, Washington, DC 20523, USA.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA.

出版信息

Contraception. 2016 Jan;93(1):32-43. doi: 10.1016/j.contraception.2015.09.002. Epub 2015 Sep 16.

Abstract

OBJECTIVES

Worldwide, women face sexual and reproductive health (SRH) risks including unintended pregnancy and sexually transmitted infections (STIs) including HIV. Multipurpose prevention technologies (MPTs) combine protection against two or more SRH risks into one product. Male and female condoms are the only currently available MPT products, but several other forms of MPTs are in development. We examined the global distribution of selected SRH issues to determine where various risks have the greatest geographical overlap.

STUDY DESIGN

We examined four indicators relevant to MPTs in development: HIV prevalence, herpes simplex virus type 2 prevalence (HSV-2), human papillomavirus prevalence (HPV) and the proportion of women with unmet need for modern contraception. Using ArcGIS Desktop, we mapped these indicators individually and in combination on choropleth and graduated symbol maps. We conducted a principal components analysis to reduce data and enable visual mapping of all four indicators on one graphic to identify overlap.

RESULTS

Our findings document the greatest overlapping risks in Sub-Saharan Africa, and we specify countries in greatest need by specific MPT indication.

CONCLUSIONS

These results can inform strategic planning for MPT introduction, market segmentation and demand generation; data limitations also highlight the need for improved (non-HIV) STI surveillance globally.

IMPLICATIONS

MPTs are products in development with the potential to empower women to prevent two or more SRH risks. Geographic analysis of overlapping SRH risks demonstrates particularly high need in Sub-Saharan Africa. This study can help to inform strategic planning for MPT introduction, market segmentation and demand generation.

摘要

目标

在全球范围内,女性面临性与生殖健康(SRH)风险,包括意外怀孕和包括艾滋病毒在内的性传播感染(STIs)。多功能预防技术(MPTs)将针对两种或更多种SRH风险的防护功能整合到一种产品中。男用和女用避孕套是目前仅有的MPT产品,但其他几种形式的MPT也在研发中。我们研究了选定的SRH问题的全球分布情况,以确定各种风险在哪些地区具有最大的地理重叠。

研究设计

我们研究了与正在研发的MPTs相关的四个指标:艾滋病毒感染率、2型单纯疱疹病毒感染率(HSV - 2)、人乳头瘤病毒感染率(HPV)以及有现代避孕需求未得到满足的女性比例。使用ArcGIS Desktop软件,我们分别并综合地在分级统计图和分级符号地图上绘制了这些指标。我们进行了主成分分析以简化数据,并能够在一张图表上直观地绘制所有四个指标,以识别重叠情况。

结果

我们的研究结果表明,撒哈拉以南非洲地区面临的风险重叠最为严重,并且我们根据特定的MPT适应症确定了最急需的国家。

结论

这些结果可为MPTs的引入、市场细分和需求产生的战略规划提供参考;数据限制也凸显了全球改善(非艾滋病毒)性传播感染监测的必要性。

启示

MPTs是正在研发的产品,有可能使女性有能力预防两种或更多种SRH风险。对SRH风险重叠情况的地理分析表明,撒哈拉以南非洲地区的需求尤为迫切。本研究有助于为MPTs的引入、市场细分和需求产生的战略规划提供参考。

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