1 Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, North Carolina.
2 Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
J Womens Health (Larchmt). 2019 May;28(5):665-672. doi: 10.1089/jwh.2018.7001. Epub 2019 Jan 4.
Multipurpose prevention technologies (MPTs) are being developed to simultaneously protect women from unintended pregnancy and sexually transmitted infections (STIs) or human immunodeficiency virus. This study aims to determine MPT characteristics desired by young women in the United States (U.S.). This is a cross-sectional national survey administered online by MTurk. Eligibility criteria included female sex, age 18-29 years, U.S. residence, and sexual activity with a male partner in the past 3 months. MPT characteristics were rated for importance. Odds ratios were generated to explore associations between demographics, sexual behaviors, and prior contraceptive use and likelihood of using various MPT formulations. Of 835 women, the largest proportion reported being likely to use MPTs in the form of injectables (45.6%), followed by vaginal gels (33.7%), vaginal rings (26.3%) and diaphragms (17.3%). Women with prior experience using a specific method of contraception appeared more likely to try an MPT of the same form. Women concerned about STIs and unwanted pregnancy, or with a history of such undesirable outcomes, expressed higher likelihood of use for a broad range of products. Women indicated that safety and efficacy at preventing pregnancy were the most important product characteristics when choosing an MPT. MPTs in the form of injectables are most highly desired, but many women would use vaginal methods, highlighting the importance of developing different delivery methods. Women desire safety and emphasize contraceptive efficacy over infection prevention. MPT preferences must be considered during product development to promote future acceptance among young women in the U.S.
多用途预防技术(MPTs)正在被开发出来,以同时保护女性免受意外怀孕和性传播感染(STIs)或人类免疫缺陷病毒的侵害。本研究旨在确定美国年轻女性对 MPT 的特征需求。这是一项通过 MTurk 在线进行的横断面全国性调查。入选标准包括女性、年龄 18-29 岁、美国居民和过去 3 个月与男性伴侣发生性行为。对 MPT 的特征进行了重要性评分。生成了比值比来探讨人口统计学、性行为和先前避孕方法的使用与使用各种 MPT 制剂的可能性之间的关联。在 835 名女性中,最大比例的人表示可能会使用注射剂形式的 MPT(45.6%),其次是阴道凝胶(33.7%)、阴道环(26.3%)和阴道隔膜(17.3%)。有特定避孕方法使用经验的女性似乎更有可能尝试相同形式的 MPT。关注性传播感染和意外怀孕或有此类不良后果史的女性表示,更有可能使用广泛的产品。女性表示,在选择 MPT 时,安全性和有效性是预防怀孕的最重要产品特征。以注射剂形式的 MPT 最受欢迎,但许多女性会使用阴道方法,这突出了开发不同给药方法的重要性。女性希望安全,并强调避孕效果而不是预防感染。在产品开发过程中必须考虑 MPT 偏好,以促进未来在美国年轻女性中的接受度。