• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

富含细胞的脂肪抽吸物关节成形术:治疗第一掌腕关节关节炎的新方法。

Cell-Enriched Lipoaspirate Arthroplasty: A Novel Approach to First Carpometacarpal Joint Arthritis.

作者信息

Bohr Stefan, Rennekampff Hans Oliver, Pallua Norbert

机构信息

1 Department of Plastic and Hand Surgery - Burn Center, University Clinics RWTH, Aachen, Germany.

出版信息

Hand Surg. 2015 Oct;20(3):479-81. doi: 10.1142/S0218810415720259.

DOI:10.1142/S0218810415720259
PMID:26388016
Abstract

We report a novel, minimal invasive technique for the treatment of symptomatic arthritis of the carpometacarpal (CMC) joint of the thumb, here termed Cell-Enriched Liposaspirate Arthroplasty (CELA). For CELA, autologous fat tissue was harvested using standard liposuction technique followed by an extra-corporal cellular enrichment step. Finally, 1 ml of cell-enriched lipoaspirate was injected into the CMC-joint. Following CELA, the treated patient became pain free within five weeks with a follow-up of 12 months. We conclude that CELA performed on selected cases of arthritis of finger joints such as the basal joint of the thumb has the potential to greatly reduce or delay the necessity for more invasive procedures which tend to improve symptoms of pain at the cost of grip strength and range-of-motion.

摘要

我们报告了一种新颖的微创技术,用于治疗拇指腕掌(CMC)关节的症状性关节炎,在此称为富细胞脂肪抽吸物关节成形术(CELA)。对于CELA,使用标准抽脂技术采集自体脂肪组织,随后进行体外细胞富集步骤。最后,将1毫升富细胞脂肪抽吸物注入CMC关节。接受CELA治疗后,在12个月的随访中,治疗的患者在五周内疼痛消失。我们得出结论,对选定的手指关节关节炎病例(如拇指基部关节)进行CELA,有可能大大减少或延迟进行更具侵入性手术的必要性,而这些侵入性手术往往以握力和活动范围为代价来改善疼痛症状。

相似文献

1
Cell-Enriched Lipoaspirate Arthroplasty: A Novel Approach to First Carpometacarpal Joint Arthritis.富含细胞的脂肪抽吸物关节成形术:治疗第一掌腕关节关节炎的新方法。
Hand Surg. 2015 Oct;20(3):479-81. doi: 10.1142/S0218810415720259.
2
Little finger carpometacarpal arthroplasty technique and result in 3 cases.3例小指腕掌关节置换术的技术与结果
J Hand Surg Am. 2014 Sep;39(9):1734-8. doi: 10.1016/j.jhsa.2014.06.014. Epub 2014 Jul 29.
3
The use of the Artelon CMC Spacer for osteoarthritis of the basal joint of the thumb.Artelon CMC间隔器在拇指掌指关节骨关节炎中的应用。
J Hand Ther. 2014 Apr-Jun;27(2):122-5; quiz 126. doi: 10.1016/j.jht.2013.12.001. Epub 2013 Dec 4.
4
A Technique for the Management of Concomitant Scaphotrapezoid Arthritis in Patients With Thumb Metacarpotrapezial Arthritis: Interposition Arthroplasty With a Capitate Suture Anchor.一种治疗拇指掌腕关节关节炎患者合并舟大多角关节炎的技术:使用头状骨缝合锚钉的间置关节成形术。
Tech Hand Up Extrem Surg. 2017 Jun;21(2):71-74. doi: 10.1097/BTH.0000000000000155.
5
Soft tissue interposition arthroplasty for osteoarthritis of the carpometacarpal joint of the thumb.
Acta Orthop Scand. 1980 Oct;51(5):767-71. doi: 10.3109/17453678008990872.
6
[Joint replacement surgery of the wrist, the distal radioulnar joint, and the hand].[腕关节、桡尺远侧关节及手部的关节置换手术]
Handchir Mikrochir Plast Chir. 2012 Oct;44(5):280-92. doi: 10.1055/s-0032-1323736. Epub 2012 Sep 3.
7
An alternative suspension technique after trapeziectomy for advanced thumb carpometacarpal osteoarthritis.晚期拇指腕掌关节骨关节炎行大多角骨切除术后的一种替代性悬吊技术。
Tech Hand Up Extrem Surg. 2012 Sep;16(3):132-4. doi: 10.1097/BTH.0b013e3182567c3a.
8
Ligament reconstruction arthroplasty for primary thumb carpometacarpal osteoarthritis (weilby technique): prospective cohort study.原发性拇指腕掌关节骨关节炎的韧带重建关节成形术(韦尔比技术):前瞻性队列研究
J Hand Surg Am. 2009 Oct;34(8):1393-401. doi: 10.1016/j.jhsa.2009.06.019. Epub 2009 Sep 6.
9
Bilateral arthroscopic tendon interposition arthroplasty of the thumb carpometacarpal joint in a patient with Ehlers-Danlos syndrome: a case report.1例患有埃勒斯-当洛综合征患者的拇指腕掌关节双侧关节镜下肌腱间置关节成形术:病例报告
J Hand Surg Am. 2005 Jul;30(4):673-6. doi: 10.1016/j.jhsa.2005.01.003.
10
Thumb carpometacarpal joint resurfacing with autologous ear cartilage.自体耳软骨用于拇指腕掌关节表面置换
Ann Plast Surg. 2014 May;72(5):521-8. doi: 10.1097/SAP.0b013e3182650ce4.

引用本文的文献

1
Prospective Treatment of First Carpometacarpal Osteoarthritis With Autologous Fat Transfer.自体脂肪移植对第一掌腕关节骨关节炎的前瞻性治疗
Plast Reconstr Surg Glob Open. 2025 Apr 25;13(4):e6713. doi: 10.1097/GOX.0000000000006713. eCollection 2025 Apr.
2
Arthroscopy with Lipoaspirate and Plasma Infiltration Using Adipose-Derived Stem Cells Plus Platelet-Rich Plasma: Harvesting and Injection for Arthroscopic Treatment of Cartilage Defects of the Knee.采用脂肪来源干细胞加富血小板血浆的关节镜检查联合脂肪抽吸物与血浆浸润:用于膝关节软骨缺损关节镜治疗的采集与注射
Arthrosc Tech. 2023 Nov 20;12(12):e2265-e2271. doi: 10.1016/j.eats.2023.07.055. eCollection 2023 Dec.
3
Effects of Intra-Articular Autologous Adipose Micrograft for the Treatment of Osteoarthritis in Dogs: A Prospective, Randomized, Controlled Study.
关节内自体脂肪微移植治疗犬骨关节炎的效果:一项前瞻性、随机、对照研究。
Animals (Basel). 2022 Jul 20;12(14):1844. doi: 10.3390/ani12141844.
4
Evaluation of Adipose Cell-Based Therapies for the Treatment of Thumb Carpometacarpal Joint Osteoarthritis.基于脂肪细胞的治疗方法治疗拇指腕掌关节骨关节炎的评估。
Biomolecules. 2022 Mar 20;12(3):473. doi: 10.3390/biom12030473.
5
New Trends in Injection-Based Therapy for Thumb-Base Osteoarthritis: Where Are We and where Are We Going?拇指基底关节骨关节炎注射治疗的新趋势:我们现状如何,又将走向何方?
Front Pharmacol. 2021 Apr 13;12:637904. doi: 10.3389/fphar.2021.637904. eCollection 2021.
6
Autologous Fat Transplantation for Thumb Carpometacarpal Joint Osteoarthritis (Liparthroplasty): A Case Series with Two Years of Follow-UP.自体脂肪移植治疗拇指腕掌关节骨关节炎(脂肪成形术):一项为期两年随访的病例系列研究
J Clin Med. 2020 Dec 31;10(1):113. doi: 10.3390/jcm10010113.
7
Autologous fat transplantation for the treatment of trapeziometacarpal joint osteoarthritis.自体脂肪移植治疗第一腕掌关节骨关节炎
Orthop Rev (Pavia). 2020 Jun 25;12(Suppl 1):8666. doi: 10.4081/or.2020.8666. eCollection 2020 Jun 29.
8
Optimal management of thumb basal joint arthritis: challenges and solutions.拇指腕掌关节关节炎的最佳管理:挑战与解决方案
Orthop Res Rev. 2017 Nov 23;9:93-99. doi: 10.2147/ORR.S138809. eCollection 2017.
9
Arthroscopic Synovectomy Combined with Autologous Fat Grafting in Early Stages of CMC Osteoarthritis of the Thumb.关节镜下滑膜切除术联合自体脂肪移植治疗拇指第一掌腕关节骨关节炎早期
J Wrist Surg. 2018 Apr;7(2):165-171. doi: 10.1055/s-0037-1604045. Epub 2017 Jul 20.
10
Development of Synthetic and Natural Materials for Tissue Engineering Applications Using Adipose Stem Cells.利用脂肪干细胞开发用于组织工程应用的合成材料和天然材料
Stem Cells Int. 2016;2016:5786257. doi: 10.1155/2016/5786257. Epub 2016 Feb 10.