Komesu M C, Lopes R A, Petenusci S O, Silva-Netto C R, Campos G M, Paula-Lopes O V
Rev Faculdade Odontol Lins. 1989 Jan-Jun;2(1):11-20.
A decrease in rat submandibular gland parenchyma could be observed with increasing age, consequent to an apparent increase in the proportion of intralobular ducts. Signs of acinar atrophy were noted with nuclei of smaller volume. A great variety of nuclear sizes and shapes was also observed. The blood vessels were smaller, and the connective tissue was increased. These histological data were confirmed in part by application of the technique of Chalkley. The granulous duct cell height is smaller in old animals.
随着年龄的增长，可观察到大鼠下颌下腺实质减少，这是由于小叶内导管比例明显增加所致。观察到腺泡萎缩的迹象，细胞核体积变小。还观察到各种各样的核大小和形状。血管变小，结缔组织增加。这些组织学数据部分通过Chalkley技术得到证实。老年动物的颗粒导管细胞高度较小。
