Manninen Marko, Pankakoski Maiju, Gissler Mika, Suvisaari Jaana
National Institute for Health and Welfare, Mannerheimintie 166, 00300 Helsinki, Finland.
Child Adolesc Psychiatry Ment Health. 2015 Sep 2;9:46. doi: 10.1186/s13034-015-0078-z. eCollection 2015.
Conduct problems during adolescence are associated with an elevated mortality risk. This study investigated the mortality rate, causes of death, and changes over time in a Finnish residential school (RS) population.
All adolescents (N = 885, M/F = 594/291, age mean 15.2 years at baseline) residing in the RS system in 1991, 1996, 2001, and 2006 and matched controls were included in a register-based study with a follow-up time of up to 22 years.
The all-cause mortality rate for people with an RS background was 6.7 % compared to 1.0 % in the controls (Hazard Ratio HR = 6.95, 95 % 4.66-10.37, p < 0.001). 8.1 % of the RS boys had died compared to 2.2 % of the girls (HR = 2.2, p = 0.02). The HR for substance-related death was 24.31 (95 % CI 9.3-65.53, P < 0.001), for suicide 7.23 (95 % CI 3.24-16.11, P < 0.001) and for other external causes 5.45 (95 % CI 2.41-12.36, P < 0.001) compared to controls. Mortality peaked among RS boys at approximately 25 years, whereas for girls it peaked after 30 years.
Adolescents with severe disruptive behavior problems have a seven-fold risk for premature adult-age death compared to matched controls. The most common causes for death were avoidable, substance-related followed by suicide. Effective treatment of mental and substance use related problems during and after the placement is needed to reduce mortality.
青少年期的行为问题与死亡风险升高有关。本研究调查了芬兰寄宿学校(RS)人群的死亡率、死亡原因及随时间的变化情况。
将1991年、1996年、2001年和2006年居住在RS系统中的所有青少年(N = 885,男/女 = 594/291,基线时平均年龄15.2岁)及匹配的对照组纳入一项基于登记的研究,随访时间长达22年。
有RS背景者的全因死亡率为6.7%,而对照组为1.0%(风险比HR = 6.95,95% 4.66 - 10.37,p < 0.001)。RS组中8.1%的男孩死亡,而女孩为2.2%(HR = 2.2,p = 0.02)。与对照组相比,与物质相关死亡的HR为24.31(95%可信区间9.3 - 65.53,P < 0.001),自杀的HR为7.23(95%可信区间3.24 - 16.11,P < 0.001),其他外部原因的HR为5.45(95%可信区间2.41 - 12.36,P < 0.001)。RS组男孩的死亡率在约25岁时达到峰值,而女孩在30岁后达到峰值。
与匹配的对照组相比,有严重破坏性行为问题的青少年过早成年死亡的风险高出7倍。最常见的死亡原因是可避免的、与物质相关的,其次是自杀。在安置期间及之后,需要对精神和物质使用相关问题进行有效治疗以降低死亡率。