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在一所针对行为障碍的寄宿学校就读的青少年在成年早期有较高的死亡风险。

Adolescents in a residential school for behavior disorders have an elevated mortality risk in young adulthood.

作者信息

Manninen Marko, Pankakoski Maiju, Gissler Mika, Suvisaari Jaana

机构信息

National Institute for Health and Welfare, Mannerheimintie 166, 00300 Helsinki, Finland.

出版信息

Child Adolesc Psychiatry Ment Health. 2015 Sep 2;9:46. doi: 10.1186/s13034-015-0078-z. eCollection 2015.

Abstract

BACKGROUND

Conduct problems during adolescence are associated with an elevated mortality risk. This study investigated the mortality rate, causes of death, and changes over time in a Finnish residential school (RS) population.

METHODS

All adolescents (N = 885, M/F = 594/291, age mean 15.2 years at baseline) residing in the RS system in 1991, 1996, 2001, and 2006 and matched controls were included in a register-based study with a follow-up time of up to 22 years.

RESULTS

The all-cause mortality rate for people with an RS background was 6.7 % compared to 1.0 % in the controls (Hazard Ratio HR = 6.95, 95 % 4.66-10.37, p < 0.001). 8.1 % of the RS boys had died compared to 2.2 % of the girls (HR = 2.2, p = 0.02). The HR for substance-related death was 24.31 (95 % CI 9.3-65.53, P < 0.001), for suicide 7.23 (95 % CI 3.24-16.11, P < 0.001) and for other external causes 5.45 (95 % CI 2.41-12.36, P < 0.001) compared to controls. Mortality peaked among RS boys at approximately 25 years, whereas for girls it peaked after 30 years.

CONCLUSIONS

Adolescents with severe disruptive behavior problems have a seven-fold risk for premature adult-age death compared to matched controls. The most common causes for death were avoidable, substance-related followed by suicide. Effective treatment of mental and substance use related problems during and after the placement is needed to reduce mortality.

摘要

背景

青少年期的行为问题与死亡风险升高有关。本研究调查了芬兰寄宿学校(RS)人群的死亡率、死亡原因及随时间的变化情况。

方法

将1991年、1996年、2001年和2006年居住在RS系统中的所有青少年(N = 885,男/女 = 594/291,基线时平均年龄15.2岁)及匹配的对照组纳入一项基于登记的研究,随访时间长达22年。

结果

有RS背景者的全因死亡率为6.7%,而对照组为1.0%(风险比HR = 6.95,95% 4.66 - 10.37,p < 0.001)。RS组中8.1%的男孩死亡,而女孩为2.2%(HR = 2.2,p = 0.02)。与对照组相比,与物质相关死亡的HR为24.31(95%可信区间9.3 - 65.53,P < 0.001),自杀的HR为7.23(95%可信区间3.24 - 16.11,P < 0.001),其他外部原因的HR为5.45(95%可信区间2.41 - 12.36,P < 0.001)。RS组男孩的死亡率在约25岁时达到峰值,而女孩在30岁后达到峰值。

结论

与匹配的对照组相比,有严重破坏性行为问题的青少年过早成年死亡的风险高出7倍。最常见的死亡原因是可避免的、与物质相关的,其次是自杀。在安置期间及之后,需要对精神和物质使用相关问题进行有效治疗以降低死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7cc/4574605/2b86048041b5/13034_2015_78_Fig1_HTML.jpg

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