Cole Joanna C M, Moldenhauer Julie S, Berger Kelsey, Cary Mark S, Smith Haley, Martino Victoria, Rendon Norma, Howell Lori J
Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, 34th Street & Civic Center Blvd., Philadelphia, PA, 19104, USA.
Drexel University College of Medicine, 2900 West Queen Lane, Philadelphia, PA, 19129, USA.
Arch Womens Ment Health. 2016 Jun;19(3):443-53. doi: 10.1007/s00737-015-0580-6. Epub 2015 Sep 21.
The aim of the study was to determine the incidence of psychological distress among expectant women carrying fetuses with prenatal diagnosed abnormalities and their partners. A 2-year retrospective medical chart review was completed of 1032 expectant mothers carrying fetuses with a confirmed anomaly, and 788 expectant fathers, who completed the CFDT Mental Health Screening Tool. Furthermore, 19.3 % of women and 13.1 % of men reported significant post-traumatic stress symptoms, and 14 % of men and 23 % of women scored positive for a major depressive disorder. Higher risk was noted among expectant parents of younger age and minority racial/ethnic status, and women with post-college level education and current or prior use of antidepressant medications. Heightened distress was noted within fetal diagnostic subgroups including neck masses, sacrococcygeal teratomas, neurological defects, and miscellaneous diagnoses. Incorporating screening tools into prenatal practice can help clinicians better identify the potential risk for psychological distress among expectant parents within high-risk fetal settings.
本研究的目的是确定怀有产前诊断异常胎儿的孕妇及其伴侣心理困扰的发生率。对1032名怀有确诊异常胎儿的孕妇和788名准父亲进行了为期2年的回顾性病历审查,这些准父亲完成了CFDT心理健康筛查工具。此外,19.3%的女性和13.1%的男性报告有明显的创伤后应激症状,14%的男性和23%的女性在重度抑郁症筛查中呈阳性。年龄较小、少数种族/族裔身份的准父母,以及受过大学后教育、目前或以前使用过抗抑郁药物的女性风险更高。在包括颈部肿块、骶尾部畸胎瘤、神经缺陷和其他诊断在内的胎儿诊断亚组中,发现了更高程度的困扰。将筛查工具纳入产前实践可以帮助临床医生更好地识别高危胎儿情况下准父母心理困扰的潜在风险。