各向异性微柱阵列上神经突方向性和神经突伸长的控制
Control over Neurite Directionality and Neurite Elongation on Anisotropic Micropillar Arrays.
作者信息
Park Matthew, Oh Eunkyul, Seo Jeongyeon, Kim Mi-Hee, Cho Hyeoncheol, Choi Ji Yu, Lee Haiwon, Choi Insung S
机构信息
Center for Cell-Encapsulation Research, Department of Chemistry, KAIST, Daejeon, 305-701, South Korea.
Department of Chemistry, College of Natural Science, Hanyang University, Seoul, 133-791, South Korea.
出版信息
Small. 2016 Mar 2;12(9):1148-52. doi: 10.1002/smll.201501896. Epub 2015 Sep 23.
PMID:26395860
Abstract
Control over neurite orientation in primary hippocampal neurons is achieved by using interrupted, anisotropic micropillar arrays as a cell culture platform. Both neurite orientation and neurite length are controlled by a function of interpillar distance.
摘要
通过使用中断的各向异性微柱阵列作为细胞培养平台，实现了对原代海马神经元神经突方向的控制。神经突方向和神经突长度均由柱间距离的函数控制。
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