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本文引用的文献

1
Prediction of Causal Candidate Genes in Coronary Artery Disease Loci.冠状动脉疾病基因座中因果候选基因的预测
Arterioscler Thromb Vasc Biol. 2015 Oct;35(10):2207-17. doi: 10.1161/ATVBAHA.115.306108. Epub 2015 Aug 20.
2
Single-cell chromatin accessibility reveals principles of regulatory variation.单细胞染色质可及性揭示调控变异原理。
Nature. 2015 Jul 23;523(7561):486-90. doi: 10.1038/nature14590. Epub 2015 Jun 17.
3
Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation.冠心病相关的TCF21变异破坏了一个miR-224结合位点以及miRNA介导的调控。
PLoS Genet. 2014 Mar 27;10(3):e1004263. doi: 10.1371/journal.pgen.1004263. eCollection 2014 Mar.
4
Integrating GWAS and expression data for functional characterization of disease-associated SNPs: an application to follicular lymphoma.整合 GWAS 和表达数据以对疾病相关 SNP 进行功能特征分析：在滤泡性淋巴瘤中的应用。
Am J Hum Genet. 2013 Jan 10;92(1):126-30. doi: 10.1016/j.ajhg.2012.11.009. Epub 2012 Dec 13.
5
Large-scale association analysis identifies new risk loci for coronary artery disease.大规模关联分析确定了冠心病的新风险位点。
Nat Genet. 2013 Jan;45(1):25-33. doi: 10.1038/ng.2480. Epub 2012 Dec 2.

From Locus Association to Mechanism of Gene Causality: The Devil Is in the Details.

作者信息

Miller Clint L, Pjanic Milos, Quertermous Thomas

机构信息

Department of Medicine, Cardiovascular Research Institute, Stanford University School of Medicine, 300 Pasteur Drive, Stanford CA 94305.

出版信息

Arterioscler Thromb Vasc Biol. 2015 Oct;35(10):2079-2080. doi: 10.1161/ATVBAHA.115.306366.

DOI:10.1161/ATVBAHA.115.306366
PMID:26399919
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4594207/
Abstract
摘要