Ling M H, Zheng Z C, Cao P, Li Z P
Yi Chuan Xue Bao. 1989;16(6):442-7.
The 3' terminal sequence of the gene for 18S rRNA of silkworm Attacus ricini have been sequenced. Comparison of this sequence with the 18S rDNA of silkworm Bombyx mori, Drosophila melanogaster, rat and the 16S rDNA of E. coli has shown that there is a remarkable homology between them. Moreover, the stem and loop formation of 3' regions of these rDNAs are very similar. There is a conservative EcoR1 site in the 3' region of these rDNAs. These results may contribute to the understanding of the functions of the 3' end of 18S rDNA in protein synthesis, in proceeding of rRNA precursor, and to the understanding of the evolutionary relation of rDNAs.
蓖麻蚕18S rRNA基因的3'末端序列已被测序。将该序列与家蚕、黑腹果蝇、大鼠的18S rDNA以及大肠杆菌的16S rDNA进行比较,结果表明它们之间存在显著的同源性。此外,这些rDNA 3'区域的茎环结构非常相似。在这些rDNA的3'区域存在一个保守的EcoR1位点。这些结果可能有助于理解18S rDNA 3'末端在蛋白质合成、rRNA前体加工中的功能,以及有助于理解rDNA的进化关系。