Chalmers David, Cusano Antonio, Haddock Peter, Staff Ilene, Wagner Joseph
Department of Urology, University of Connecticut, Farmington, USA and Research Group, Hartford Hospital, Hartford, USA.
Urology Division, Hartford Healthcare Medical group, Hartford, USA.
Int Braz J Urol. 2015 Jul-Aug;41(4):661-8. doi: 10.1590/S1677-5538.IBJU.2014.0464.
To assess whether retinal and central nervous system (CNS) comorbidities are risk factors for complications following robotic assisted laparoscopic prostatectomy (RALP).
A retrospective review of our RALP database identified 1868 patients who underwent RALP by a single surgeon between December 10, 2003-March 14, 2014. We hypothesized that patients with preexisting retinal or CNS comorbidities were at a greater risk of suffering retinal and CNS complications following RALP. Perioperative complications and risk of recurrence were graded using the Clavien and D'Amico systems, respectively.
40 (2.1%) patients had retinal or CNS-related comorbidities, of which 15 had a history of retinal surgery and 24 had a history of cerebrovascular accident, aneurysm and/or neurosurgery. One additional patient had a history of both retinal and CNS events. Patients with retinal or CNS comorbidities were significantly older, had elevated PSA levels and CCI (Charlson Comorbidity Index) scores than the control group. Blood loss, length of stay, surgical duration, BMI, diagnostic Gleason score and T-stage were not statistically different between groups. No retinal or CNS complications occurred in either group. The distribution of patients between D'Amico risk categories was not statistically different between the groups. There was also no difference in the incidence of total complications between the groups.
RALP-associated retinal and CNS complications are rare. While our RALP database is large, the cohort of patients with retinal or CNS-related comorbidities was relatively small. Our dataset suggests retinal and CNS pathology presents no greater risk of suffering from perioperative complications following RALP.
评估视网膜和中枢神经系统(CNS)合并症是否为机器人辅助腹腔镜前列腺切除术(RALP)后并发症的危险因素。
对我们的RALP数据库进行回顾性分析,确定了2003年12月10日至2014年3月14日期间由一名外科医生实施RALP的1868例患者。我们假设,术前存在视网膜或CNS合并症的患者在RALP后发生视网膜和CNS并发症的风险更高。围手术期并发症和复发风险分别采用Clavien和D'Amico系统进行分级。
40例(2.1%)患者存在视网膜或CNS相关合并症,其中15例有视网膜手术史,24例有脑血管意外、动脉瘤和/或神经外科手术史。另有1例患者既有视网膜又有CNS事件史。有视网膜或CNS合并症的患者比对照组年龄显著更大,PSA水平和CCI(Charlson合并症指数)评分更高。两组间失血、住院时间、手术时长、BMI、诊断性Gleason评分和T分期无统计学差异。两组均未发生视网膜或CNS并发症。两组间D'Amico风险类别患者的分布无统计学差异。两组间总并发症发生率也无差异。
RALP相关的视网膜和CNS并发症罕见。虽然我们的RALP数据库规模较大,但视网膜或CNS相关合并症患者队列相对较小。我们的数据集表明,视网膜和CNS病变在RALP后发生围手术期并发症的风险并不更高。