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全球消除风疹和先天性风疹综合征的进展 - 2000-2014 年。

Global Progress Toward Rubella and Congenital Rubella Syndrome Control and Elimination - 2000-2014.

出版信息

MMWR Morb Mortal Wkly Rep. 2015 Sep 25;64(37):1052-5. doi: 10.15585/mmwr.mm6437a5.

Abstract

Rubella virus usually causes a mild fever and rash in children and adults. However, infection during pregnancy, especially during the first trimester, can result in miscarriage, fetal death, stillbirth, or a constellation of congenital malformations known as congenital rubella syndrome (CRS). In 2011, the World Health Organization (WHO) updated guidance on the preferred strategy for introduction of rubella-containing vaccine (RCV) into national routine immunization schedules, including an initial vaccination campaign usually targeting children aged 9 months-15 years . The Global Vaccine Action Plan endorsed by the World Health Assembly in 2012 and the Global Measles and Rubella Strategic Plan (2012-2020) published by Measles and Rubella Initiative partners in 2012 both include goals to eliminate rubella and CRS in at least two WHO regions by 2015, and at least five WHO regions by 2020 (2,3). This report updates a previous report and summarizes global progress toward rubella and CRS control and elimination during 2000-2014. As of December 2014, RCV had been introduced in 140 (72%) countries, an increase from 99 (51%) countries in 2000 (for this report, WHO member states are referred to as countries). Reported rubella cases declined 95%, from 670,894 cases in 102 countries in 2000 to 33,068 cases in 162 countries in 2014, although reporting is inconsistent. To achieve the 2020 Global Vaccine Action Plan rubella and CRS elimination goals, RCV introduction needs to continue as country criteria indicating readiness are met, and rubella and CRS surveillance need to be strengthened to ensure that progress toward elimination can be measured.

摘要

风疹病毒通常会导致儿童和成人轻度发热和皮疹。然而,怀孕期间的感染,尤其是在妊娠早期,可能导致流产、胎儿死亡、死产,或导致先天性风疹综合征(CRS)等一系列先天性畸形。2011 年,世界卫生组织(WHO)更新了关于将含风疹疫苗(RCV)纳入国家常规免疫计划的首选策略的指南,包括针对 9 个月至 15 岁儿童的初始疫苗接种运动。2012 年世界卫生大会批准的全球疫苗行动计划和 2012 年麻疹和风疹倡议合作伙伴发布的全球麻疹和风疹战略计划(2012-2020 年)都包括到 2015 年在至少两个世卫组织区域消除风疹和 CRS,并到 2020 年在至少五个世卫组织区域消除风疹和 CRS(2、3)的目标。本报告更新了之前的报告,总结了 2000 年至 2014 年期间全球在控制和消除风疹和 CRS 方面的进展。截至 2014 年 12 月,RCV 已在 140 个(72%)国家推出,高于 2000 年的 99 个(51%)国家(为本报告目的,世卫组织会员国称为国家)。报告的风疹病例减少了 95%,从 2000 年 102 个国家的 670,894 例降至 2014 年 162 个国家的 33,068 例,但报告情况不一致。为实现 2020 年全球疫苗行动计划风疹和 CRS 消除目标,需要继续推出 RCV,同时满足表明准备就绪的国家标准,并加强风疹和 CRS 监测,以确保能够衡量消除进展情况。

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