El Haj Mohamad, Gély-Nargeot Marie-Christine, Raffard Stéphane
Laboratoire SCALab UMR CNRS 9193- University of Lille Nord de France, France.
Epsylon Laboratory, EA 4556, University Montpellier III, Montpellier, France.
J Alzheimers Dis. 2015;48(2):529-36. doi: 10.3233/JAD-150467.
Destination memory, or the ability to remember the destination to whom a piece of information was addressed, is found to be compromised in Alzheimer's disease (AD). Our paper investigated the relationship between destination memory and theory of mind in AD since both destination memory and theory of mind are social abilities that require processing attributes of interlocutors. Mild AD participants and controls were administered tasks tapping destination memory, affective theory of mind, and 1st and 2nd order cognitive theory of mind. Relative to controls, AD participants showed compromise in destination memory and 2nd order cognitive theory of mind, but preserved performance on affective and 1st order cognitive theory of mind. Significant correlations were observed between destination memory, and 1st and 2nd order cognitive theory of mind in AD participants and controls. By demonstrating a relationship between compromises in 2nd order theory of mind and in destination memory, our work highlights links between social cognition and memory functioning in AD.
目的记忆，即记住信息所针对对象的能力，被发现会在阿尔茨海默病（AD）中受损。我们的论文研究了AD中目的记忆与心理理论之间的关系，因为目的记忆和心理理论都是需要处理对话者属性的社交能力。对轻度AD参与者和对照组进行了测试目的记忆、情感心理理论以及一阶和二阶认知心理理论的任务。相对于对照组，AD参与者在目的记忆和二阶认知心理理论方面表现受损，但在情感和一阶认知心理理论方面表现保留。在AD参与者和对照组中，目的记忆与一阶和二阶认知心理理论之间观察到显著相关性。通过证明二阶心理理论受损与目的记忆受损之间的关系，我们的研究突出了AD中社会认知与记忆功能之间的联系。
