Ryu Jong-Hyun, Kim Tae-Hoon, Jeong Chang-Won, Jun Hong-Young, Heo Dong-Woon, Lee Jinseok, Kim Kyong-Woo, Yoon Kwon-Ha
Imaging Science-based Lung and Bone Disease Research Center, Wonkwang University, Iksan, Jeonbuk, Korea.
Nanofocusray, Deokjin-gu, Jeonju, Jeonbuk, Korea.
J Xray Sci Technol. 2015;23(4):473-80. doi: 10.3233/XST-150502.
Mobile computed tomography (CT) with a cone-beam source is increasingly used in the clinical field. Mobile cone-beam CT (CBCT) has great merits; however, its clinical utility for brain imaging has been limited due to problems including scan time and image quality.
The aim of this study was to develop a dedicated mobile volumetric CBCT for obtaining brain images, and to optimize the imaging protocol using a brain phantom.
The mobile volumetric CBCT system was evaluated with regards to scan time and image quality, measured as signal-to-noise-ratio (SNR), contrast-to-noise-ratio (CNR), spatial resolution (10% MTF), and effective dose. Brain images were obtained using a CT phantom.
The CT scan took 5.14 s at 360 projection views. SNR and CNR were 5.67 and 14.5 at 120 kV/10 mA. SNR and CNR values showed slight improvement as the x-ray voltage and current increased (p < 0.001). Effective dose and 10% MTF were 0.92 mSv and 360 μ m at 120 kV/10 mA. Various intracranial structures were clearly visible in the brain phantom images.
Using this CBCT under optimal imaging acquisition conditions, it is possible to obtain human brain images with low radiation dose, reproducible image quality, and fast scan time.
带有锥形束源的移动计算机断层扫描（CT）在临床领域的应用日益广泛。移动锥形束CT（CBCT）具有诸多优点；然而，由于扫描时间和图像质量等问题，其在脑成像方面的临床应用受到了限制。
本研究旨在开发一种用于获取脑部图像的专用移动容积CBCT，并使用脑部模型优化成像方案。
对移动容积CBCT系统进行扫描时间和图像质量评估，图像质量通过信噪比（SNR）、对比噪声比（CNR）、空间分辨率（10%调制传递函数）和有效剂量来衡量。使用CT模型获取脑部图像。
在360个投影视图下，CT扫描耗时5.14秒。在120 kV/10 mA时，SNR和CNR分别为5.67和14.5。随着X射线电压和电流的增加，SNR和CNR值略有改善（p < 0.001）。在120 kV/10 mA时，有效剂量和10%调制传递函数分别为0.92 mSv和360μm。在脑部模型图像中，各种颅内结构清晰可见。
在最佳成像采集条件下使用这种CBCT，可以获得低辐射剂量、可重复的图像质量和快速扫描时间的人脑图像。
