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高频超声对大鼠心脏的三维成像及其在肌纤维方向包绕中的应用

3D imaging of rat hearts by high frequency ultrasound and its application in myofiber orientation wrapping.

作者信息

Qin Xulei, Wang Silun, Shen Ming, Zhang Xiaodong, Lerakis Stamatios, Wagner Mary B, Fei Baowei

机构信息

Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA.

Yerkes National Primate Research Center, Emory University, Atlanta, GA.

出版信息

Proc SPIE Int Soc Opt Eng. 2015;9419. doi: 10.1117/12.2082326.

DOI:10.1117/12.2082326
PMID:26412926
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4581442/
Abstract

Cardiac ultrasound plays an important role in the imaging of hearts in basic cardiovascular research and clinical examinations. 3D ultrasound imaging can provide the geometry or motion information of the heart. Especially, the wrapping of cardiac fiber orientations to the ultrasound volume could supply useful information on the stress distributions and electric action spreading. However, how to acquire 3D ultrasound volumes of the heart of small animals for cardiac fiber wrapping is still a challenging problem. In this study, we provide an approach to acquire 3D ultrasound volumes of the rat hearts . The comparison between both and geometries indicated 90.1% Dice similarity. In this preliminary study, the evaluations of the cardiac fiber orientation wrapping errors were 24.7° for the acute angle error and were 22.4° for the inclination angle error. This 3D ultrasound imaging and fiber orientation estimation technique have potential applications in cardiac imaging.

摘要

心脏超声在基础心血管研究和临床检查中对心脏成像起着重要作用。三维超声成像能够提供心脏的几何形状或运动信息。特别是,心脏纤维方向围绕超声容积的情况可以提供有关应力分布和电活动传播的有用信息。然而,如何获取用于心脏纤维包裹研究的小动物心脏的三维超声容积仍然是一个具有挑战性的问题。在本研究中,我们提供了一种获取大鼠心脏三维超声容积的方法。两种几何形状之间的比较表明骰子相似度为90.1%。在这项初步研究中,心脏纤维方向包裹误差的评估结果为锐角误差为24.7°,倾斜角误差为22.4°。这种三维超声成像和纤维方向估计技术在心脏成像中具有潜在应用。

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