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帕金森病中的平衡问题

What Is Wrong with Balance in Parkinson's Disease?

机构信息

Department of Neurology, College of Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.

Department of Neurology, School of Medicine, Oregon Health & Science University, Portland, OR, USA ; Portland VA Medical Center, Portland, OR, USA.

出版信息

J Mov Disord. 2015 Sep;8(3):109-14. doi: 10.14802/jmd.15018. Epub 2015 Sep 10.

DOI:10.14802/jmd.15018
PMID:26413237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4572660/
Abstract

Postural instability and resulting falls are major factors determining quality of life, morbidity, and mortality in individuals with Parkinson's disease (PD). A better understanding of balance impairments would improve management of balance dysfunction and prevent falls in patients with PD. The effects of bradykinesia, rigidity, impaired proprioception, freezing of gait and attention on postural stability in patients with idiopathic PD have been well characterized in laboratory studies. The purpose of this review is to systematically summarize the types of balance impairments contributing to postural instability in people with PD.

摘要

姿势不稳和由此导致的跌倒,是影响帕金森病(PD)患者生活质量、发病率和死亡率的主要因素。更好地了解平衡障碍将有助于管理 PD 患者的平衡功能障碍和预防跌倒。在实验室研究中,已经很好地描述了运动迟缓、僵硬、本体感觉受损、步态冻结和注意力对特发性 PD 患者姿势稳定性的影响。本综述的目的是系统地总结导致 PD 患者姿势不稳定的平衡障碍类型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04b7/4572660/2382b79db883/jmd-8-3-109f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04b7/4572660/c3811b5b9bc1/jmd-8-3-109f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04b7/4572660/67039c2f1334/jmd-8-3-109f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04b7/4572660/b87b1fdd8661/jmd-8-3-109f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04b7/4572660/2382b79db883/jmd-8-3-109f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04b7/4572660/c3811b5b9bc1/jmd-8-3-109f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04b7/4572660/67039c2f1334/jmd-8-3-109f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04b7/4572660/b87b1fdd8661/jmd-8-3-109f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04b7/4572660/2382b79db883/jmd-8-3-109f4.jpg

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Effects of deep brain stimulation in the subthalamic nucleus or globus pallidus internus on step initiation in Parkinson disease: laboratory investigation.
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Sci Rep. 2025 Jul 1;15(1):20643. doi: 10.1038/s41598-025-07009-2.
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The vestibulo-ocular and vestibulospinal reflexes minimally impact the freezing of gait in patients with early-to-moderate Parkinson's disease.前庭眼反射和前庭脊髓反射对早中期帕金森病患者的步态冻结影响极小。
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