Kerkeni Walid, Rebai Mohamed H, Bouzouita Abderrazak, Chakroun Marouene, Slama Riadh Ben, Abdallah Taieb Ben, Derouiche Amine, Chebil Mohamed
Urology Department, Charles Nicolle Hospital, Tunis, Tunisia.
Department of Nephrology and Internal Medicine, Charles Nicolle Hospital, Tunis, Tunisia.
Arab J Urol. 2015 Sep;13(3):221-4. doi: 10.1016/j.aju.2015.06.002. Epub 2015 Jul 9.
To analyse the effects of baseline body mass index (BMI) on the postoperative and remote consequences of nephrectomy in living kidney donors, as body weight is conventionally used as an exclusion criterion for kidney donation and a BMI of <35 kg/m(2) is often required.
We retrospectively studied 189 living-related kidney donors who had their nephrectomy between 1986 and 2009 in our urology department. We recorded the BMI at the time of donation, and analysed variables after surgery, and clinico-biological factors remotely. The effect of the initial BMI after surgery and much later after nephrectomy was assessed.
The mean follow-up was 9.28 years. The mean (range) BMI at the time of donation was 26.5 (18.5-41.1) kg/m(2); 33% of donors were overweight (BMI 25-30) and 21% were obese (⩾30), with 10.5% having a BMI of >35 kg/m(2). The duration of hospitalisation was not related to the BMI. There was no significant difference between the mean BMI of donors with a simple postoperative history and donors who had complications after surgery. Among obese donors, only 7.7% had a complication, which was a surgical-site infection in all cases. The baseline BMI was higher among donors who maintained normal renal function and no proteinuria than in donors with impaired renal function and/or proteinuria; the difference was not significant. The occurrence of hypertension or diabetes was independent of baseline BMI. Donors with dyslipidaemia had no significantly greater baseline BMI than those with no dyslipidaemia.
The BMI at the time of kidney donation does not seem to influence the short- or long-term consequences of nephrectomy in living donors.
分析基线体重指数（BMI）对活体肾供体肾切除术后及远期后果的影响，因为体重通常被用作肾脏捐赠的排除标准，且常要求BMI<35kg/m²。
我们回顾性研究了1986年至2009年在我院泌尿外科接受肾切除术的189例活体亲属肾供体。我们记录了捐赠时的BMI，并分析了术后变量以及远期的临床生物学因素。评估了肾切除术后即刻及很久之后初始BMI的影响。
平均随访时间为9.28年。捐赠时的平均（范围）BMI为26.5（18.5 - 41.1）kg/m²；33%的供体超重（BMI 25 - 30），21%肥胖（≥30），10.5%的BMI>35kg/m²。住院时间与BMI无关。单纯术后病史的供体与术后有并发症的供体的平均BMI之间无显著差异。在肥胖供体中，只有7.7%发生了并发症，所有病例均为手术部位感染。肾功能正常且无蛋白尿的供体的基线BMI高于肾功能受损和/或有蛋白尿的供体；差异不显著。高血压或糖尿病的发生与基线BMI无关。血脂异常的供体的基线BMI与无血脂异常的供体相比无显著更高。
肾脏捐赠时的BMI似乎不影响活体供体肾切除的短期或长期后果。
