Abd El Salam Z
Egypt Dent J. 1989 Oct;35(4):347-58.
Five patients suffering from cancerous lesions in oral and pharyngeal areas, were studied in this research and in comparing with two normal cases. The major salivary glands were indirectly exposed to irradiation where the patients receiving a radiation therapy which is Cobalt(60). Scintigraphy was performed for both patients and normal cases to visualize the functional capacity and activity of the salivary glands following the high radiation doses. It was found from the results that the dynamic and static scintigrams of the salivary glands which were in the field of irradiation appeared faint in visualization and delayed in perfusion. Also an increase in concentration of the radiotracer 99m Tc-pertechnetate in the gland after physiologic stimulation. This attributed to fibrosis and dysfunction in the glands as a results of the previous irradiation.
本研究对5例口腔和咽部患有癌性病变的患者进行了研究，并与2例正常病例进行了比较。主要唾液腺因患者接受钴（60）放射治疗而间接受到照射。对患者和正常病例均进行了闪烁扫描，以观察高剂量辐射后唾液腺的功能能力和活性。结果发现，受照射区域内唾液腺的动态和静态闪烁图在可视化方面显得模糊，灌注延迟。此外，生理刺激后腺体中放射性示踪剂99m锝高锝酸盐的浓度增加。这归因于先前照射导致的腺体纤维化和功能障碍。
