Dolcini F, Sabbatini R C, Paolinelli C
Dent Cadmos. 1989 Oct 31;57(16):98-102.
This study valued by Eosinophilic Index (EI) or cellular maturation index the behaviour of oral mucosa cells undergoing stimulus of hormones during menstrual cycle, as well as vaginal cells according to a supposition by several Authors. Specimens by scraping of oral mucosa cells in female patients selected by standards of regular menstrual cycle and absence of any oral pathology or dental prosthesis, actually showed EI changes according to cycle stage and rate of hormonal effect probably. On the other hand, specimens by scraping or oral mucosa cells in male patients showed constant EI rates during monthly cycle. Being statistical study not significant because of little series of specimens--it's difficult to select a lot of women and to control them during their whole menstrual cycle working in a small surgery! -, yet Authors confirm results of previous studies by different Authors. If the relationship between cellular maturation of oral cells and effect of hormones during menstrual cycle resulted, it could be possible further on to investigate, for example, the behaviour of epithelial cells being in any periodontal pocket undergoing stimulus of female hormones.
本研究通过嗜酸性粒细胞指数(EI)或细胞成熟指数评估了月经周期中受激素刺激的口腔黏膜细胞以及阴道细胞的行为,这是根据多位作者的推测进行的。通过刮取符合月经周期规律且无任何口腔病变或假牙标准的女性患者口腔黏膜细胞样本,实际上可能显示出EI根据周期阶段和激素作用速率而发生变化。另一方面,男性患者刮取的口腔黏膜细胞样本在每月周期中显示出恒定的EI率。由于样本数量较少,统计学研究无显著意义——在小型诊所工作时,很难挑选出大量女性并在其整个月经周期进行监测!——但作者证实了不同作者先前研究的结果。如果月经周期中口腔细胞的细胞成熟与激素作用之间的关系得到证实,那么进一步研究例如处于任何牙周袋中的上皮细胞在受到女性激素刺激时的行为将成为可能。