Pereira Danielle M, Khan Azizuddin
a Psychophysiology Laboratory, Department of Humanities and Social Sciences , Indian Institute of Technology Bombay , Mumbai , India.
Laterality. 2016;21(2):161-76. doi: 10.1080/1357650X.2015.1090444. Epub 2015 Sep 28.
Difficulty shifting attention away from negative stimuli once engaged is a well-established cognitive bias observed in depression. This study attempted to determine whether this impaired disengagement of attention is lateralized in the brain. Thirty depressed and 30 control participants performed an attention disengagement task wherein the valence of the stimulus and the visual field was presented. The depressed group had longer reaction times than the control group, indicative of the typical cognitive and psychomotor slowing seen in depression. The effect of visual field presentation on the ability to disengage attention however was different for controls as compared to the patients. In controls, a distinct right hemisphere advantage was seen for disengaging attention which is in line with research that has identified right hemisphere structures as the seat of behavioural inhibition. In the depressed group, however, this right hemisphere advantage was not observed.
一旦注意力被负面刺激吸引，就难以转移，这是抑郁症中一种公认的认知偏差。本研究试图确定这种注意力脱离受损在大脑中是否存在偏侧化。30名抑郁症患者和30名对照组参与者进行了一项注意力脱离任务，其中呈现了刺激的效价和视野。抑郁症组的反应时间比对照组更长，这表明抑郁症中典型的认知和精神运动迟缓。然而，与患者相比，视野呈现对对照组注意力脱离能力的影响有所不同。在对照组中，注意力脱离存在明显的右半球优势，这与将右半球结构确定为行为抑制部位的研究一致。然而，在抑郁症组中，未观察到这种右半球优势。
