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注意缺陷多动障碍成人视觉空间注意力的不对称半球控制

Asymmetrical hemispheric control of visual-spatial attention in adults with attention deficit hyperactivity disorder.

作者信息

Epstein Jeffrey N, Conners C Keith, Erhardt Drew, March John S, Swanson James M

机构信息

Duke U.

出版信息

Neuropsychology. 1997 Oct;11(4):467-473. doi: 10.1037/0894-4105.11.4.467.

DOI:10.1037/0894-4105.11.4.467
PMID:9345690
Abstract

As neuropsychological mechanisms for attention have been hypothesized to be located in the right hemisphere of the brain, several investigators have begun to conceptualize attention deficit hyperactivity disorder (ADHD)-related attentional deficits as involving right-hemispheric abnormalities. The authors evaluated and compared adult patients diagnosed with ADHD with a non-ADHD group of patients using a chronometric visual-spatial attention task that is sensitive to hemispheric differences in efficiency of information processing. Reaction times across different cuing conditions, cue-target delays, and visual fields were assessed. When participants' attention was misdirected with cues in the right visual field and attention had to be switched to a target on the left visual field, there was a longer delay among ADHD adults than non-ADHD adults, specifically when the interval between the cue and target was 800 ms as compared with 100 ms. This specific pattern of dysfunction was interpreted as a difficulty with maintaining attention possibly associated with anterior attention mechanisms in the right hemisphere.

摘要

由于注意力的神经心理学机制被假定位于大脑右半球,一些研究者已开始将注意力缺陷多动障碍(ADHD)相关的注意力缺陷概念化为涉及右半球异常。作者使用对信息处理效率的半球差异敏感的计时视觉空间注意力任务,对被诊断患有ADHD的成年患者与非ADHD患者组进行了评估和比较。评估了不同提示条件、提示-目标延迟和视野下的反应时间。当参与者的注意力被右视野中的提示误导,且注意力必须转移到左视野中的目标时,ADHD成年人比非ADHD成年人有更长的延迟,特别是当提示与目标之间的间隔为800毫秒时,而相比之下100毫秒时则不然。这种特定的功能障碍模式被解释为可能与右半球前部注意力机制相关的维持注意力困难。

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