Smirnova I P, Larichev V F, Shneider Yu A
Antibiot Khimioter. 2015;60(3-4):3-5.
The antitumor effect of L-lysine-α-oxidase from the culture fluid of Trichoderma harzianum Rifai F-180 was investigated for the first time. The in vitro studies revealed its high activity on a model of the forest-spring encephalitis virus and no activity against the Sindbis, Western Nile, Tyaginya and Dhori viruses.
首次研究了哈茨木霉 Rifai F-180 培养液中 L-赖氨酸-α-氧化酶的抗肿瘤作用。体外研究表明,它对森林脑炎病毒模型具有高活性,而对辛德毕斯病毒、西尼罗河病毒、蒂亚吉尼亚病毒和多里病毒无活性。