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用酶响应聚合物和表面活性剂编程的液晶界面。

Liquid Crystal Interfaces Programmed with Enzyme-Responsive Polymers and Surfactants.

机构信息

Department of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, Wisconsin, 53706, USA.

Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California, 92093, USA.

出版信息

Small. 2015 Nov 18;11(43):5747-51. doi: 10.1002/smll.201502137. Epub 2015 Sep 29.

DOI:10.1002/smll.201502137
PMID:26418129
Abstract

Synthesis of biologically active peptide-polymer amphiphiles (PPAs), and characterization of assemblies formed by PPAs at the interfaces of liquid crystal (LC) microdroplets, is shown to permit the use of PPAs in strategies that can trigger ordering transitions in LC microdroplets in response to targeted biomolecular events.

摘要

展示了具有生物活性的肽-聚合物两亲物(PPAs)的合成,以及 PPAs 在液晶(LC)微滴界面形成的组装体的特性,这使得 PPAs 可以用于在针对生物分子事件的靶向刺激下引发 LC 微滴中有序转变的策略。

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