Long R
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1989;24(1):34-6, 63.
One hundred and seventy patients with nasal polyps were studied. According to the history, skin tests with inhalant allergens, determination of serum nasal secretion and polyp fluid IgE, and X-ray films of nasal sinuses, it was suggested that 93.5% of them might have complicated with allergic diseases, 87.7% with sinusitis. A relationship between local IgE production and the eosinophil infiltration of polyps existed. This study suggests that allergic process acting locally on the mucous membrane of the nose is the etiologic factor and bacterial allergy probably contributes to the development of nasal polyps. In order to prevent the recurrence after polypectomy, antiallergic management combined with antibiotics and drainage of infected sinuses may be necessary in most cases.
对170例鼻息肉患者进行了研究。根据病史、吸入性变应原皮肤试验、血清、鼻分泌物及息肉液IgE测定以及鼻窦X线片，提示其中93.5%可能合并变应性疾病，87.7%合并鼻窦炎。息肉局部IgE产生与嗜酸性粒细胞浸润之间存在关联。本研究提示，局部作用于鼻黏膜的变应性过程是病因，细菌变应可能促使鼻息肉形成。为防止息肉切除术后复发，多数情况下可能需要抗变应治疗联合抗生素及引流感染的鼻窦。
