Lozano-Calderón Santiago A, Chen Neal
Department of Orthopaedic Surgery, Musculoskeletal Oncology Service, Beth Israel Deaconess Medical Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Department of Orthopaedic Surgery, Hand and Upper Extremity Service Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Curr Rev Musculoskelet Med. 2015 Dec;8(4):324-33. doi: 10.1007/s12178-015-9306-7.
The proximal humerus is the second most common location of primary bone sarcomas and a frequent location of benign locally aggressive primary osseous tumors. In contrast to other locations, tumors in this region impose significant challenges for local control and reconstruction. This is due to glenohumeral joint anatomic characteristics such as lack of intrinsic stability and dependence on dynamic and static stabilizers. In addition, the close proximity of the axillary nerve and axillary vascular bundle places these at risk of resection when attaining local control. Allograft prosthetic composites (APCs) of the proximal humerus are one of the methods for mobile reconstruction. This modality presents lower fracture rates when compared to osteoarticular allografts and lower rates of subluxation and instability than endoprosthesis. Recent literature documents a trend for superior functional outcome at comparable complication rates. APC reconstruction is an important tool in the orthopedic oncologist armamentarium.
肱骨近端是原发性骨肉瘤的第二常见发病部位,也是良性局部侵袭性原发性骨肿瘤的常见发病部位。与其他部位不同,该区域的肿瘤在局部控制和重建方面面临重大挑战。这是由于盂肱关节的解剖特征,如缺乏内在稳定性以及依赖动态和静态稳定器。此外,腋神经和腋血管束位置紧邻,在实现局部控制进行切除时会使其面临风险。肱骨近端的同种异体移植假体复合物(APC)是可活动重建的方法之一。与骨关节同种异体移植相比,这种方式骨折率较低,与假体相比半脱位和不稳定发生率较低。近期文献表明,在并发症发生率相当的情况下,功能结局有更好的趋势。APC重建是骨科肿瘤医生治疗手段中的一项重要工具。