Pilkonis Paul A, Yu Lan, Dodds Nathan E, Johnston Kelly L, Lawrence Suzanne M, Hilton Thomas F, Daley Dennis C, Patkar Ashwin A, McCarty Dennis
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States.
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States.
Drug Alcohol Depend. 2015 Nov 1;156:184-192. doi: 10.1016/j.drugalcdep.2015.09.008. Epub 2015 Sep 21.
Two item banks for substance use were developed as part of the Patient-Reported Outcomes Measurement Information System (PROMIS(®)): severity of substance use and positive appeal of substance use.
Qualitative item analysis (including focus groups, cognitive interviewing, expert review, and item revision) reduced an initial pool of more than 5300 items for substance use to 119 items included in field testing. Items were written in a first-person, past-tense format, with 5 response options reflecting frequency or severity. Both 30-day and 3-month time frames were tested. The calibration sample of 1336 respondents included 875 individuals from the general population (ascertained through an internet panel) and 461 patients from addiction treatment centers participating in the National Drug Abuse Treatment Clinical Trials Network.
Final banks of 37 and 18 items were calibrated for severity of substance use and positive appeal of substance use, respectively, using the two-parameter graded response model from item response theory (IRT). Initial calibrations were similar for the 30-day and 3-month time frames, and final calibrations used data combined across the time frames, making the items applicable with either interval. Seven-item static short forms were also developed from each item bank.
Test information curves showed that the PROMIS item banks provided substantial information in a broad range of severity, making them suitable for treatment, observational, and epidemiological research in both clinical and community settings.
作为患者报告结局测量信息系统(PROMIS(®))的一部分,开发了两个物质使用项目库:物质使用严重程度和物质使用积极吸引力。
定性项目分析(包括焦点小组、认知访谈、专家评审和项目修订)将最初超过5300个物质使用项目的库减少到119个纳入现场测试的项目。项目采用第一人称、过去时态编写,有5个反映频率或严重程度的回答选项。对30天和3个月的时间框架都进行了测试。1336名受访者的校准样本包括875名来自普通人群的个体(通过互联网小组确定)和461名来自参与国家药物滥用治疗临床试验网络的成瘾治疗中心的患者。
分别使用项目反应理论(IRT)的两参数等级反应模型对37个和18个项目的最终库进行了物质使用严重程度和物质使用积极吸引力的校准。30天和3个月时间框架的初始校准相似,最终校准使用了跨时间框架合并的数据,使这些项目适用于任何一个时间段。还从每个项目库中开发了7项静态简表。
测试信息曲线表明,PROMIS项目库在广泛的严重程度范围内提供了大量信息,使其适用于临床和社区环境中的治疗、观察和流行病学研究。