Denardo S J, Oye R K, Bellamy P E
Division of General Internal Medicine and Health Services Research, UCLA School of Medicine 90024-1736.
Crit Care Med. 1989 Jan;17(1):4-6. doi: 10.1097/00003246-198901000-00002.
We reviewed the ICU courses of 50 bone marrow transplant recipients treated for respiratory problems. Seven of nine postoperative patients survived compared to one of 40 patients with progressive interstitial pneumonia. Nonsurvivors accounted for 94% of the ICU days, 98% of intubated days, and 99% of blood products used. All survivors were extubated within 4 days. Intensive respiratory care is effective for patients with readily reversible causes of respiratory failure, but is generally futile for patients with progressive interstitial pneumonia. We recommend providing these patients with realistic prognostic estimates early in their treatment.
我们回顾了50例因呼吸问题接受治疗的骨髓移植受者在重症监护病房（ICU）的病程。9例术后患者中有7例存活，而40例进行性间质性肺炎患者中仅有1例存活。非存活者占ICU住院天数的94%、插管天数的98%以及所用血液制品的99%。所有存活者均在4天内拔管。强化呼吸护理对呼吸衰竭病因易于逆转的患者有效，但对进行性间质性肺炎患者通常无效。我们建议在这些患者治疗早期就为其提供实际的预后评估。
