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一名重症类风湿关节炎患者的肢端水疱和大疱

Acral vesicles and bullae in a patient with severe rheumatoid arthritis.

作者信息

Soza Gabriela M, Griffin John R

机构信息

Texas A&M College of Medicine, Bryan, Texas (Soza) and the Department of Dermatology, Baylor University Medical Center at Dallas (Griffin).

出版信息

Proc (Bayl Univ Med Cent). 2015 Oct;28(4):461-2. doi: 10.1080/08998280.2015.11929308.

Abstract

We present the case of a 56-year-old black woman with rheumatoid arthritis who developed worsening fatigue, fever, weight loss, and a vesiculobullous skin eruption while being treated with certolizumab pegol for her arthritis. Microscopic findings confirmed the diagnosis of a neutrophilic dermatosis.

摘要

我们报告了一例56岁患有类风湿性关节炎的黑人女性病例,她在使用聚乙二醇化赛妥珠单抗治疗关节炎时,出现了疲劳加重、发热、体重减轻以及水疱大疱性皮肤疹。显微镜检查结果确诊为嗜中性皮肤病。

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本文引用的文献

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Neutrophilic dermatosis: disease mechanism and treatment.嗜中性皮病:发病机制与治疗
Curr Opin Hematol. 2015 Jan;22(1):23-9. doi: 10.1097/MOH.0000000000000100.
2
Neutrophilic dermatoses as systemic diseases.作为系统性疾病的嗜中性皮肤病
Clin Dermatol. 2014 May-Jun;32(3):376-88. doi: 10.1016/j.clindermatol.2013.11.004. Epub 2013 Dec 3.
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Rheumatoid neutrophilic dermatosis with tense blister formation: a case report and review of the literature.
Australas J Dermatol. 2014 Feb;55(1):e12-4. doi: 10.1111/j.1440-0960.2012.00963.x. Epub 2012 Oct 25.
5
A bullous neutrophilic dermatosis in a patient with severe rheumatoid arthritis and monoclonal IgA gammopathy.
J Am Acad Dermatol. 2004 Aug;51(2 Suppl):S94-6. doi: 10.1016/j.jaad.2003.12.054.
7
Rheumatoid neutrophilic dermatitis associated with pyoderma gangrenosum.
Br J Dermatol. 2000 Jun;142(6):1246-8. doi: 10.1046/j.1365-2133.2000.03565.x.

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