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显微镜下多血管炎导致弥漫性肺泡出血和快速进行性肾小球肾炎。

Microscopic polyangiitis causing diffuse alveolar hemorrhage and rapidly progressive glomerulonephritis.

作者信息

Lababidi Mohamad Hani, Odigwe Chibuzo, Okolo Chukwuka, Elhassan Ahmed, Iroegbu Nkemakolam

机构信息

Department of Medicine, St. Joseph Hospital, Chicago, Illinois.

出版信息

Proc (Bayl Univ Med Cent). 2015 Oct;28(4):469-71. doi: 10.1080/08998280.2015.11929311.

DOI:10.1080/08998280.2015.11929311
PMID:26424944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4569227/
Abstract

Diffuse alveolar hemorrhage complicating small vessel vasculitis is a life-threatening emergency and should be considered in the differential diagnosis of patients who develop rapidly progressive dyspnea with alveolar opacities on chest imaging. In these patients, the coexistence of pulmonary and renal involvement suggests a multisystem disease. We present a case of a man who presented to our hospital with diffuse alveolar hemorrhage, severe anemia, and rapidly progressive glomerulonephritis.

摘要

弥漫性肺泡出血并发小血管炎是一种危及生命的急症,对于胸部影像学显示有肺泡浸润且迅速进展为呼吸困难的患者进行鉴别诊断时应考虑此病。在这些患者中,肺部和肾脏受累提示存在多系统疾病。我们报告一例男性患者,他因弥漫性肺泡出血、严重贫血和快速进展性肾小球肾炎前来我院就诊。

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本文引用的文献

1
A retrospective study of microscopic polyangiitis patients presenting with pulmonary fibrosis in China.在中国,对表现出肺纤维化的显微镜下多血管炎患者进行的回顾性研究。
BMC Pulm Med. 2014 Jan 28;14:8. doi: 10.1186/1471-2466-14-8.
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Rapidly progressive pulmonary haemorrhage in a case of microscopic polyangiitis.显微镜下多血管炎一例中的快速进行性肺出血
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N Engl J Med. 2010 Jul 15;363(3):221-32. doi: 10.1056/NEJMoa0909905.
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Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis.利妥昔单抗与环磷酰胺治疗抗中性粒细胞胞质抗体相关性肾血管炎。
N Engl J Med. 2010 Jul 15;363(3):211-20. doi: 10.1056/NEJMoa0909169.
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Diffuse alveolar hemorrhage: diagnosing it and finding the cause.弥漫性肺泡出血:诊断及病因查找
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Pulmonary involvement in microscopic polyangiitis.显微镜下多血管炎的肺部受累情况。
Curr Opin Pulm Med. 2005 Sep;11(5):447-51. doi: 10.1097/01.mcp.0000170520.63874.fb.
9
Primary systemic vasculitis: clinical features and mortality.原发性系统性血管炎:临床特征与死亡率
QJM. 2005 Feb;98(2):97-111. doi: 10.1093/qjmed/hci015. Epub 2005 Jan 17.
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Rapidly progressive antineutrophil cytoplasm antibodies associated with pulmonary-renal syndrome in a 10-year-old girl.一名10岁女孩中与肺肾综合征相关的快速进展性抗中性粒细胞胞浆抗体
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