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多节段颈椎滑膜软骨瘤病的外科治疗

Surgical Management of Multi-Level Cervical Spine Synovial Chondromatosis.

作者信息

Mirza Farhan Arshad, Vasquez Raul Alberto

机构信息

Department of Neurosurgery, University of Kentucky, Lexington, KY, USA.

出版信息

Asian J Neurosurg. 2021 May 28;16(2):367-371. doi: 10.4103/ajns.AJNS_157_20. eCollection 2021 Apr-Jun.

DOI:10.4103/ajns.AJNS_157_20
PMID:34268166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8244714/
Abstract

Cervical synovial chondromatosis is a benign condition which most commonly affects the knee joint. The involvement of the spinal column is rare, with only a few reports in the literature describing surgical treatment for compressive spinal lesions. Given the rarity of this condition, the best treatment methodology is yet to be established. We describe the case of a 38-year-old female who presented with progressively worsening myeloradicular symptoms localizing to the cervical spinal cord. Imaging revealed a multilevel osseous and epidural lesion involving the subaxial cervical spine. A computed tomography-guided biopsy was performed to obtain a diagnosis to aid further treatment planning. Subsequently, surgical decompression and stabilization were performed after which the patient made an excellent recovery. She continues to do well at 2 years follow-up. Cervical synovial chondromatosis is a rare condition which can present with pain, radiculopathy, and/or myelopathy. Surgical treatment should focus on complete resection, decompression, and stabilization with arthrodesis and fusion to prevent recurrence. We propose that the lack of motion provided by stabilization and fusion after gross total resection prevents disease recurrence.

摘要

颈椎滑膜软骨瘤病是一种良性疾病,最常累及膝关节。脊柱受累罕见,文献中仅有少数报道描述了针对压迫性脊柱病变的手术治疗。鉴于这种疾病的罕见性,最佳治疗方法尚未确立。我们描述了一名38岁女性的病例,她出现了逐渐加重的脊髓神经根症状,定位在颈髓。影像学检查显示颈下颈椎有一个多节段的骨质和硬膜外病变。进行了计算机断层扫描引导下的活检以获得诊断,辅助进一步的治疗规划。随后,进行了手术减压和固定,术后患者恢复良好。在2年的随访中,她情况一直良好。颈椎滑膜软骨瘤病是一种罕见疾病,可表现为疼痛、神经根病和/或脊髓病。手术治疗应侧重于彻底切除、减压以及通过关节固定术和融合术进行固定,以防止复发。我们认为,在大体全切术后通过固定和融合提供的缺乏活动可防止疾病复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd91/8244714/d8b6962eb4e6/AJNS-16-367-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd91/8244714/58e0ac03b2ca/AJNS-16-367-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd91/8244714/4008694e3394/AJNS-16-367-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd91/8244714/da642415c194/AJNS-16-367-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd91/8244714/d8b6962eb4e6/AJNS-16-367-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd91/8244714/58e0ac03b2ca/AJNS-16-367-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd91/8244714/4008694e3394/AJNS-16-367-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd91/8244714/da642415c194/AJNS-16-367-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd91/8244714/d8b6962eb4e6/AJNS-16-367-g004.jpg

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本文引用的文献

1
Synovial chondromatosis presenting as an epidural mass.表现为硬膜外肿块的滑膜软骨瘤病。
Surg Neurol Int. 2015 Aug 31;6(Suppl 14):S388-90. doi: 10.4103/2152-7806.163961. eCollection 2015.
2
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Korean J Spine. 2012 Sep;9(3):253-6. doi: 10.14245/kjs.2012.9.3.253. Epub 2012 Sep 30.
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J Pediatr Orthop B. 2015 May;24(3):255-61. doi: 10.1097/BPB.0000000000000123.
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Synovial chondrosarcoma arising in synovial chondromatosis.滑膜软骨瘤病中发生的滑膜软骨肉瘤。
Sarcoma. 2014;2014:647939. doi: 10.1155/2014/647939. Epub 2014 Mar 5.
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Synovial chondromatosis of the cervical spine: a case report and review of the literature.
Pediatr Dev Pathol. 2014 May-Jun;17(3):221-5. doi: 10.2350/14-02-1445-CR.1. Epub 2014 Mar 20.
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Synovial chondromatosis of spine: case report and review of the literature.脊柱滑膜软骨瘤病:病例报告及文献复习
Ann Clin Lab Sci. 2010 Winter;40(1):71-4.
7
Vertebral synovial chondromatosis. Report of two cases and review of the literature.
J Neurosurg Spine. 2004 Sep;1(2):211-8. doi: 10.3171/spi.2004.1.2.0211.
8
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Spine (Phila Pa 1976). 2003 Oct 1;28(19):E396-400. doi: 10.1097/01.BRS.0000085161.79758.23.
9
Synovial chondromatosis of the cervical spine. Case illustration.
J Neurosurg. 2002 Jul;97(1 Suppl):150. doi: 10.3171/spi.2002.97.1.0150.
10
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