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发热诱发的Brugada综合征。

Fever-Induced Brugada Syndrome.

作者信息

Manohar Sandhya, Dahal Binaya Raman, Gitler Bernard

机构信息

Montefiore New Rochelle Hospital, New Rochelle, NY, USA.

出版信息

J Investig Med High Impact Case Rep. 2015 Mar 23;3(1):2324709615577414. doi: 10.1177/2324709615577414. eCollection 2015 Jan-Mar.

DOI:10.1177/2324709615577414
PMID:26425637
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4586913/
Abstract

Brugada syndrome is increasingly recognized as a cause of sudden cardiac death. Many of these patients do not get diagnosed due its dynamic and often hidden nature. We have come a long way in understanding the disease process, and its electrophysiology appears to be intimately linked with sodium channel mutations or disorders. The cardiac rhythm in these patients can deteriorate into fatal ventricular arrhythmias. This makes it important for the clinician to be aware of the conditions in which arrhythmogenicity of Brugada syndrome is revealed or even potentiated. We present such an instance where our patient's Brugada syndrome was unmasked by fever.

摘要

布加综合征越来越被认为是心源性猝死的一个原因。由于其动态性且常常隐匿的特性,许多此类患者未得到诊断。在理解该疾病过程方面我们已经取得了长足进展,并且其电生理学似乎与钠通道突变或紊乱密切相关。这些患者的心律可恶化为致命性室性心律失常。这使得临床医生了解揭示甚至增强布加综合征致心律失常性的情况变得很重要。我们呈现这样一个病例,即我们的患者因发热而暴露了布加综合征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c89c/4586913/b65fe9e5028e/10.1177_2324709615577414-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c89c/4586913/42a7bdd29c11/10.1177_2324709615577414-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c89c/4586913/b65fe9e5028e/10.1177_2324709615577414-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c89c/4586913/42a7bdd29c11/10.1177_2324709615577414-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c89c/4586913/b65fe9e5028e/10.1177_2324709615577414-fig2.jpg

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本文引用的文献

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HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes: document endorsed by HRS, EHRA, and APHRS in May 2013 and by ACCF, AHA, PACES, and AEPC in June 2013.遗传性原发性心律失常综合征患者诊断与管理的HRS/EHRA/APHRS专家共识声明:2013年5月由HRS、EHRA和APHRS认可,2013年6月由ACCF、AHA、PACES和AEPC认可。
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J Atr Fibrillation. 2017 Apr 30;9(6):1554. doi: 10.4022/jafib.1554. eCollection 2017 Apr-May.
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