Alkabie Samir, Bello Brian, Martinez Roberto F, Geis W Peter, Ballo Michael S
Northwest Hospital, Randallstown, MD, USA ; Saba University School of Medicine, Devens, MA, USA.
Northwest Hospital, Randallstown, MD, USA ; Sinai Hospital, Baltimore, MD, USA.
J Investig Med High Impact Case Rep. 2015 Mar 23;3(1):2324709615577415. doi: 10.1177/2324709615577415. eCollection 2015 Jan-Mar.
Metastatic malignant tumors that originate from occult primaries are defined as "cancers of unknown origin." We herein present the case of a 59-year-old man who presented with small bowel perforation secondary to metastatic adenocarcinoma of an unknown primary site. Imaging exhibited two pulmonary nodules, neither of which was dominant, along with mediastinal and retroperitoneal lymphadenopathy. Immunohistochemical profiling of the small bowel biopsy specimens revealed the tumor was most likely pulmonary in origin.
起源于隐匿原发灶的转移性恶性肿瘤被定义为“原发灶不明的癌症”。我们在此报告一例59岁男性患者，其因原发部位不明的转移性腺癌导致小肠穿孔。影像学检查显示有两个肺结节，均不具有优势，同时伴有纵隔和腹膜后淋巴结肿大。小肠活检标本的免疫组化分析显示，该肿瘤很可能起源于肺部。
