蕈样肉芽肿和塞扎里综合征的临床病理特征及治疗的新进展
New aspects of the clinicopathological features and treatment of mycosis fungoides and Sézary syndrome.
作者信息
Furue Masutaka, Kadono Takafumi
机构信息
Department of Dermatology, Kyushu University, Fukuoka, Japan.
Department of Dermatology, St Marianna University School of Medicine, Kanagawa, Japan.
出版信息
J Dermatol. 2015 Oct;42(10):941-4. doi: 10.1111/1346-8138.13083.
Mycosis fungoides and Sézary syndrome are T-helper (Th)2-skewed cutaneous lymphomas. The clinical course of mycosis fungoides is classically indolent, manifesting as patches, plaques and tumors. Along with their progression, Th2 dominance tends to be accelerated. In this review, we discuss the epidemiology, clinicopathogenetic features and therapeutic approaches in mycosis fungoides and Sézary syndrome.
蕈样肉芽肿和塞扎里综合征是Th2型皮肤淋巴瘤。蕈样肉芽肿的临床病程通常较为缓慢，表现为斑片、斑块和肿瘤。随着病情进展，Th2优势往往会加速。在本综述中，我们讨论了蕈样肉芽肿和塞扎里综合征的流行病学、临床病理特征及治疗方法。
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