Dermatology, IRCCS, S. Orsola-Malpighi Polyclinic, 40100 Bologna, Italy.
Department of Specialistic, Diagnostic and Experimental Medicine (DIMES), Alma Mater Studiorum, University of Bologna, 40100 Bologna, Italy.
Cells. 2021 Oct 17;10(10):2780. doi: 10.3390/cells10102780.
Mycosis fungoides (MF) and Sezary Syndrome (SS) are the most common cutaneous T-cell lymphomas. It has been hypothesized that the interaction between the immune system, cutaneous cells, and neoplastic elements may play a role in MF/SS pathogenesis and progression.
This paper aims to revise in a narrative way our current knowledge of the microenvironment's role in MF/SS.
Literature data support a possible implication of microenvironment cells in MF/SS pathogenesis and progression, opening up new therapeutic avenues.
蕈样肉芽肿（MF）和塞扎里综合征（SS）是最常见的皮肤 T 细胞淋巴瘤。有人假设免疫系统、皮肤细胞和肿瘤成分之间的相互作用可能在 MF/SS 的发病机制和进展中发挥作用。
本文旨在以叙述的方式修订我们目前对微环境在 MF/SS 中的作用的认识。
文献数据支持微环境细胞在 MF/SS 的发病机制和进展中可能具有一定的作用，为新的治疗方法开辟了道路。
Zotero 插件