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门诊内镜血管溶解激光手术治疗的并发症与失败情况

Complications and Failures of Office-Based Endoscopic Angiolytic Laser Surgery Treatment.

作者信息

Del Signore Anthony G, Shah Rupali N, Gupta Nikita, Altman Kenneth W, Woo Peak

机构信息

Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, New York 10029.

Department of Otolaryngology-Head and Neck Surgery, University of North Carolina, Chapel Hill, North Carolina 27599.

出版信息

J Voice. 2016 Nov;30(6):744-750. doi: 10.1016/j.jvoice.2015.08.022.

Abstract

OBJECTIVES/HYPOTHESIS: Although office-based laser surgery applications for benign and premalignant lesions of the larynx are appealing, there are scant data on their complications and failures. We review office-based angiolytic laser surgery in patients with benign laryngeal pathology for rates of complication and failure.

STUDY DESIGN

Retrospective chart review.

METHODS

Two hundred fifty-five patients who underwent in-office angiolytic laser surgery treatment over 4 years were reviewed. The criteria for complications and failures were based on postprocedure stroboscopy and clinical findings.

RESULTS

The majority of patients had unilateral disease, which included polyps (46%), leukoplakia (14%), papilloma (13%), scar (12%), and varix (11%). There were 382 laser treatments, of which 56% were by pulsed potassium titanyl phosphate laser. Average energy delivery was lesion specific, with papilloma receiving the most (mean 351 J) and varices receiving the least (mean 53 J) energy. Most in-office treatments were tolerated well. Four percent of patients had complications including stiffness, atrophy, and transient but prolonged hyperemia. Twenty-seven percent of patients required multiple laser treatments. Multiple treatments were more likely in papilloma and leukoplakia.

CONCLUSIONS

While in-office laser therapy for benign vocal fold lesions is appealing, repeated treatment due to incomplete resolution may be needed. Risks of transient and long-term complications are low but real. Patient selection and standardized laser energy parameters may help in decreasing complications and need for repeat procedures.

摘要

目的/假设:尽管基于门诊的激光手术在治疗喉良性和癌前病变方面颇具吸引力,但关于其并发症和治疗失败情况的数据却很少。我们回顾了基于门诊的血管消融激光手术治疗喉良性病变患者的并发症发生率和治疗失败率。

研究设计

回顾性病历审查。

方法

对4年间接受门诊血管消融激光手术治疗的255例患者进行了回顾。并发症和治疗失败的标准基于术后频闪喉镜检查和临床发现。

结果

大多数患者为单侧病变,包括息肉(46%)、白斑(14%)、乳头状瘤(13%)、瘢痕(12%)和静脉曲张(11%)。共进行了382次激光治疗,其中56%采用脉冲钛酸钾磷酸激光。平均能量传递因病变而异,乳头状瘤接受的能量最多(平均351焦耳),静脉曲张接受的能量最少(平均53焦耳)。大多数门诊治疗耐受性良好。4%的患者出现并发症,包括僵硬、萎缩和短暂但持续时间较长的充血。27%的患者需要多次激光治疗。乳头状瘤和白斑患者更有可能需要多次治疗。

结论

虽然基于门诊的激光治疗良性声带病变颇具吸引力,但可能需要因治疗未完全缓解而进行重复治疗。短暂和长期并发症的风险较低但确实存在。患者选择和标准化的激光能量参数可能有助于减少并发症和重复治疗的需求。

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