Pinter-Brown Lauren C
Department of Internal Medicine, Division of Hematology-Oncology, Geffen School of Medicine, University of California, Los Angeles, 2020 Santa Monica Suite 600, Santa Monica, CA 90404, USA.
Dermatol Clin. 2015 Oct;33(4):835-40. doi: 10.1016/j.det.2015.05.003.
The diagnosis of primary cutaneous B-cell lymphoma (CBCL) requires that the search for a more widespread lymphoma has been negative. The clinical presentation, outlook, and treatment options of the common types of CBCLs, with emphasis on differences or similarities to their nodal counterparts, are discussed. Treatment may range from observation to topical therapies to systemic therapies, depending on the histology, degree and area of skin involvement, patient performance, and comorbidities. Rare lymphomas, such as intravascular large B-cell lymphoma and Epstein-Barr virus-positive cutaneous lymphoproliferations that are associated with immunodeficiency, are also briefly described.
原发性皮肤B细胞淋巴瘤（CBCL）的诊断要求排除更广泛的淋巴瘤。本文讨论了常见类型CBCL的临床表现、预后和治疗选择，重点阐述了其与淋巴结对应类型的异同。治疗方法根据组织学类型、皮肤受累程度和范围、患者身体状况及合并症，可从观察到局部治疗再到全身治疗。文中还简要描述了罕见淋巴瘤，如血管内大B细胞淋巴瘤以及与免疫缺陷相关的爱泼斯坦-巴尔病毒阳性皮肤淋巴增殖性疾病。
