Kinoshita Tomonari, Kamiyama Ikuo, Hayashi Yuichiro, Asakura Keisuke, Ohtsuka Takashi, Kohno Mitsutomo, Emoto Katsura, Nakayama Robert, Morioka Hideo, Asamura Hisao
Division of General Thoracic Surgery, Department of Surgery, Keio University School of Medicine, Tokyo, Japan.
Division of General Thoracic Surgery, Department of Surgery, Keio University School of Medicine, Tokyo, Japan.
Ann Thorac Surg. 2015 Oct;100(4):1465-7. doi: 10.1016/j.athoracsur.2014.12.107.
Spontaneous regression of tumors is very unusual and is defined as a partial or complete disappearance of metastatic tumors without any treatment. This phenomenon has been reported in almost all types of cancer. The patient was a 25-year-old woman who presented with multiple pulmonary nodules on her bilateral lungs on the annual chest roentgenograph. Simultaneously, a swelling mass on her subcutaneous inguinal region was observed. The diagnosis of the inguinal mass was extraskeletal myxoid chondrosarcoma. The inguinal mass and pulmonary nodules spontaneously regressed without any treatment after biopsy. The patient was doing well without evidence of recurrence at 1 year after the operation without any additional therapy. Our case is the first clinical one that indicated a possibility of histologic regression of extraskeletal myxoid chondrosarcoma.
肿瘤的自发消退非常罕见，其定义为未经任何治疗的转移性肿瘤部分或完全消失。几乎在所有类型的癌症中都有这种现象的报道。该患者为一名25岁女性，在年度胸部X线检查时双侧肺部出现多个肺结节。同时，在其腹股沟皮下区域观察到一个肿胀的肿块。腹股沟肿块的诊断为骨外黏液样软骨肉瘤。活检后，腹股沟肿块和肺结节未经任何治疗而自发消退。术后1年，患者情况良好，无复发迹象，未接受任何额外治疗。我们的病例是首例表明骨外黏液样软骨肉瘤可能出现组织学消退的临床病例。
