使用无标记多功能探针的miRNA的灵敏表面增强拉曼散射检测。
A sensitive SERS detection of miRNA using a label-free multifunctional probe.
作者信息
Zhang Hao, Liu Yu, Gao Jian, Zhen Junhui
机构信息
Department of Chemistry, Qilu University of Technology, Jinan 250353, China.
出版信息
Chem Commun (Camb). 2015 Dec 7;51(94):16836-9. doi: 10.1039/c5cc06225j. Epub 2015 Oct 5.
PMID:26434544
Abstract
A novel surface enhanced Raman scattering (SERS) detection method is fabricated for miRNA based on a smart multifunctional probe for dual cyclical nucleic acid strand-displacement polymerization (CNDP), achieving high sensitivity, universality, rapid analysis, and good performance in real cell samples.
摘要
基于用于双循环核酸链置换聚合（CNDP）的智能多功能探针，构建了一种用于检测miRNA的新型表面增强拉曼散射（SERS）检测方法，该方法在真实细胞样本中具有高灵敏度、通用性、快速分析能力和良好性能。
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