Pati Susmita, Ladowski Kristi L, Wong Angie T, Huang Jiayu, Yang Jie
Department of Pediatrics, Stony Brook University, Stony Brook, NY, United States.
Department of Pediatrics, Stony Brook University, Stony Brook, NY, United States.
Vaccine. 2015 Nov 17;33(46):6257-63. doi: 10.1016/j.vaccine.2015.09.070. Epub 2015 Oct 2.
Disparities in childhood vaccination rates persist.
To evaluate the impact of an enriched medical home intervention using community health workers on improving immunization adherence among young children.
The intervention group received home visits from trained community health workers to support families in adhering to recommended care while the comparison group received usual care (i.e. no home visits/reminders). Immunization history and socio-demographic data were collected using medical records and a validated questionnaire. The doubly robust estimation of risk difference, which combines weighting via propensity score and outcome regression model, was used to compare immunization adherence rates between two groups.
Primary care practices affiliated with a suburban tertiary care academic medical center serving a socioeconomically diverse population.
The study sample included children ≤ 2 years of age at enrollment who crossed at least one age time point of 3, 7, 15, or 24 months during their 6 months post-enrollment period.
The primary outcome was age-specific immunization up-to-date status defined by CDC guidelines. The primary predictor was participation in the intervention.
The analysis included 201 children in the usual care group and 110 children in the intervention group. The usual care and intervention groups were divided into subgroups of newborn and infant/toddler to account for prior immunization history. After adjusting for differences in group characteristics, we found a significant absolute increase in the up-to-date immunization likelihood for both newborns (20.9%, p=0.01) and infants/toddlers (16.8%, p=0.01) receiving the intervention when compared to their peers receiving usual clinical care.
Our findings demonstrate the positive impact of an enriched medical home intervention using community health worker home visitation on early childhood immunization up-to-date status. With further study, this model may provide a cost-effective approach to improving childhood vaccination rates, especially for vulnerable groups.
儿童疫苗接种率的差异依然存在。
评估利用社区卫生工作者开展的强化医疗之家干预措施对提高幼儿免疫接种依从性的影响。
干预组接受经过培训的社区卫生工作者的家访,以支持家庭坚持接受推荐的护理,而对照组接受常规护理(即无家访/提醒)。使用病历和经过验证的问卷收集免疫接种史和社会人口统计学数据。采用结合倾向得分加权和结局回归模型的双重稳健风险差异估计方法,比较两组之间的免疫接种依从率。
隶属于一家郊区三级医疗学术医学中心的基层医疗诊所,服务于社会经济背景多样的人群。
研究样本包括入组时年龄≤2岁且在入组后6个月内跨越至少一个3、7、15或24月龄年龄时间点的儿童。
主要结局是根据美国疾病控制与预防中心(CDC)指南定义的特定年龄免疫接种最新状态。主要预测因素是参与干预。
分析纳入了常规护理组的201名儿童和干预组的110名儿童。常规护理组和干预组根据既往免疫接种史分为新生儿和婴幼儿亚组。在调整组间特征差异后,我们发现与接受常规临床护理的同龄人相比,接受干预的新生儿(20.9%,p = 0.01)和婴幼儿(16.8%,p = 0.01)的最新免疫接种可能性有显著的绝对增加。
我们的研究结果表明,利用社区卫生工作者家访开展的强化医疗之家干预措施对幼儿免疫接种最新状态有积极影响。通过进一步研究,该模式可能为提高儿童疫苗接种率提供一种具有成本效益的方法,尤其是对弱势群体而言。