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以患者为中心的社区卫生工作者干预措施改善出院后结局:一项随机临床试验。

Patient-centered community health worker intervention to improve posthospital outcomes: a randomized clinical trial.

机构信息

Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia2Penn Center for Community Health Workers, University of Pennsylvania, Philadelphia3Spectrum Health Services, Inc, Philadelphia, Pennsylvania4Leonard Davis Institu.

Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia5Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia.

出版信息

JAMA Intern Med. 2014 Apr;174(4):535-43. doi: 10.1001/jamainternmed.2013.14327.

Abstract

IMPORTANCE Socioeconomic and behavioral factors can negatively influence posthospital outcomes among patients of low socioeconomic status (SES). Traditional hospital personnel often lack the time, skills, and community linkages required to address these factors. OBJECTIVE To determine whether a tailored community health worker (CHW) intervention would improve posthospital outcomes among low-SES patients. DESIGN, SETTING, AND PARTICIPANTS A 2-armed, single-blind, randomized clinical trial was conducted between April 10, 2011, and October 30, 2012, at 2 urban, academically affiliated hospitals. Of 683 eligible general medical inpatients (ie, low-income, uninsured, or Medicaid) that we screened, 237 individuals (34.7%) declined to participate. The remaining 446 patients (65.3%) were enrolled and randomly assigned to study arms. Nearly equal percentages of control and intervention group patients completed the follow-up interview (86.6% vs 86.9%). INTERVENTIONS During hospital admission, CHWs worked with patients to create individualized action plans for achieving patients' stated goals for recovery. The CHWs provided support tailored to patient goals for a minimum of 2 weeks. MAIN OUTCOMES AND MEASURES The prespecified primary outcome was completion of primary care follow-up within 14 days of discharge. Prespecified secondary outcomes were quality of discharge communication, self-rated health, satisfaction, patient activation, medication adherence, and 30-day readmission rates. RESULTS Using intention-to-treat analysis, we found that intervention patients were more likely to obtain timely posthospital primary care (60.0% vs 47.9%; P = .02; adjusted odds ratio [OR], 1.52; 95% CI, 1.03-2.23), to report high-quality discharge communication (91.3% vs 78.7%; P = .002; adjusted OR, 2.94; 95% CI, 1.5-5.8), and to show greater improvements in mental health (6.7 vs 4.5; P = .02) and patient activation (3.4 vs 1.6; P = .05). There were no significant differences between groups in physical health, satisfaction with medical care, or medication adherence. Similar proportions of patients in both arms experienced at least one 30-day readmission; however, intervention patients were less likely to have multiple 30-day readmissions (2.3% vs 5.5%; P = .08; adjusted OR, 0.40; 95% CI, 0.14-1.06). Among the subgroup of 63 readmitted patients, recurrent readmission was reduced from 40.0% vs 15.2% (P = .03; adjusted OR, 0.27; 95% CI, 0.08-0.89). CONCLUSIONS AND RELEVANCE Patient-centered CHW intervention improves access to primary care and quality of discharge while controlling recurrent readmissions in a high-risk population. Health systems may leverage the CHW workforce to improve posthospital outcomes by addressing behavioral and socioeconomic drivers of disease. TRIAL REGISTRATION clinicaltrials.gov Identifier: NCT01346462.

摘要

重要性:社会经济和行为因素可能会对社会经济地位较低的患者的出院后结果产生负面影响。传统的医院人员通常缺乏解决这些因素所需的时间、技能和社区联系。目的:确定量身定制的社区卫生工作者(CHW)干预是否会改善低收入群体患者的出院后结果。设计、地点和参与者:这是一项 2 臂、单盲、随机临床试验,于 2011 年 4 月 10 日至 2012 年 10 月 30 日在 2 家城市学术附属医院进行。在我们筛选的 683 名合格的普通住院患者(即低收入、无保险或医疗补助)中,有 237 人(34.7%)拒绝参与。其余 446 名患者(65.3%)入组并随机分配到研究组。对照组和干预组完成随访访谈的比例相近(86.6%对 86.9%)。干预措施:在住院期间,CHW 与患者合作制定实现患者康复目标的个体化行动计划。CHW 根据患者的目标提供至少 2 周的支持。主要结果和措施:预设的主要结果是在出院后 14 天内完成初级保健随访。预设的次要结果是出院沟通质量、自我报告的健康状况、满意度、患者激活、药物依从性和 30 天再入院率。结果:使用意向治疗分析,我们发现干预组患者更有可能及时获得出院后的初级保健(60.0%对 47.9%;P=0.02;调整后的优势比[OR],1.52;95%置信区间,1.03-2.23),报告高质量的出院沟通(91.3%对 78.7%;P=0.002;调整后的 OR,2.94;95%置信区间,1.5-5.8),并在心理健康方面有更大的改善(6.7 对 4.5;P=0.02)和患者激活(3.4 对 1.6;P=0.05)。两组在身体健康、医疗保健满意度或药物依从性方面没有显著差异。两组都有相当比例的患者至少经历了一次 30 天再入院;然而,干预组患者多次 30 天再入院的可能性较低(2.3%对 5.5%;P=0.08;调整后的 OR,0.40;95%置信区间,0.14-1.06)。在 63 名再入院患者的亚组中,复发性再入院率从 40.0%降至 15.2%(P=0.03;调整后的 OR,0.27;95%置信区间,0.08-0.89)。结论和相关性:以患者为中心的 CHW 干预可改善高危人群获得初级保健的机会,并提高出院沟通质量,同时控制再次入院率。医疗系统可以利用 CHW 劳动力,通过解决疾病的行为和社会经济驱动因素来改善出院后结果。试验注册:clinicaltrials.gov 标识符:NCT01346462。

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