Walk Seth T
EcoSal Plus. 2015;6(2). doi: 10.1128/ecosalplus.ESP-0002-2015.
In 2009, five monophyletic Escherichia clades were described and referred to as "cryptic" based on the inability to distinguish them from representative E. coli isolates using diagnostic biochemical reactions. Since this original publication, a number of studies have explored the genomic, transcriptomic, and phenotypic diversity of cryptic clade isolates to better understand their phylogenetic, physiological, and ecological distinctiveness with respect to previously named Escherichia species. This chapter reviews the original discovery of the cryptic clades, discusses available evidence that some are environmentally adapted, and evaluates current support for taxonomic designations of these microorganisms. The importance of these clades to clinical research, epidemiology, population genetics, and microbial speciation is also discussed.
2009年，有五个单系大肠杆菌分支被描述，并因其无法通过诊断性生化反应与代表性大肠杆菌分离株区分开来而被称为“隐匿性”。自最初发表这一研究以来，许多研究探索了隐匿性分支分离株的基因组、转录组和表型多样性，以便更好地了解它们相对于先前命名的大肠杆菌物种在系统发育、生理和生态方面的独特性。本章回顾了隐匿性分支的最初发现，讨论了一些分支适应环境的现有证据，并评估了目前对这些微生物分类命名的支持情况。还讨论了这些分支对临床研究、流行病学、群体遗传学和微生物物种形成的重要性。
