Ogbera Anthonia O, Adeleye Olufunmilayo, Solagberu Babatunde, Azenabor Alfred
Department of Medicine, Lagos State University College Of Medicine, Ikeja, Lagos, Nigeria.
Department of Medicine, Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria.
BMC Res Notes. 2015 Oct 4;8:533. doi: 10.1186/s13104-015-1423-2.
Identifying the risk factors for diabetes mellitus related foot ulceration would save more limbs from amputation. This report focuses on the determining the burden of peripheral arterial disease and neuropathy in persons with diabetes mellitus (DM).
This is a descriptive study carried out in the Diabetic Clinic of the Lagos State University Teaching Hospital in patients with DM who had no past/present history of foot ulceration. Biothesiometry was employed and ankle brachial pressure indices were measured to evaluate for neuropathy and peripheral arterial disease (PAD) respectively.
A total of 225 persons living with DM who met inclusion criteria were recruited consecutively over a 3 months period. Age range was 28-87 years with the mean [61.4 (10.8)] and median (63) years respectively. Patients symptomatic for neuropathy and PAD were 37 and 40 % respectively of the study population. An older age of >60 years and poor glycaemic control were potential predictors of neuropathy. Neuropathy and PAD occurred commonly in the seventh decade of life.
Given the fairly high proportions of neuropathy and PAD in our patients with DM, we recommend that they be routinely examined in persons with DM.
识别糖尿病相关足部溃疡的危险因素可避免更多肢体被截肢。本报告重点在于确定糖尿病患者外周动脉疾病和神经病变的负担。
这是一项描述性研究，在拉各斯州立大学教学医院糖尿病诊所对无足部溃疡既往史/现病史的糖尿病患者开展。采用生物感觉测量法并测量踝臂压力指数，分别评估神经病变和外周动脉疾病（PAD）。
在3个月期间连续招募了225名符合纳入标准的糖尿病患者。年龄范围为28 - 87岁，平均年龄[61.4（10.8）]岁，中位数为63岁。有神经病变症状和PAD症状的患者分别占研究人群的37%和40%。年龄大于60岁以及血糖控制不佳是神经病变的潜在预测因素。神经病变和PAD常见于70岁左右。
鉴于我们的糖尿病患者中神经病变和PAD的比例相当高，我们建议对糖尿病患者进行常规检查。
