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印度西北部食管癌的社会人口统计学参数:一家地区癌症中心的十年经验

Sociodemographic Parameters of Esophageal Cancer in Northwest India: A Regional Cancer Center Experience of 10 Years.

作者信息

Kapoor Akhil, Kumar Vanita, Singhal Mukesh Kumar, Nirban Raj Kumar, Beniwal Surender Kumar, Kumar Harvindra Singh

机构信息

Department of Radiation Oncology, Acharya Tulsi Regional Cancer Treatment and Research Institute, Bikaner, Rajasthan, India.

Department of Pathology, Sardar Patel Medical College and Associated Group of Hospitals, Bikaner, Rajasthan, India.

出版信息

Indian J Community Med. 2015 Oct-Dec;40(4):264-7. doi: 10.4103/0970-0218.164399.

Abstract

BACKGROUND

Despite various advances in the treatment of Esophageal Cancer (EC), being one of the least responsive tumors to cancer therapy, the overall prognosis remains poor. Therefore, it is significant to understand various sociodemographic factors associated with EC to find out various schemes for primary prevention of the disease.

MATERIALS AND METHODS

This is a retrospective analysis of medical records of the EC patients registered in the regional cancer center of northwest India from January 2003 to December 2012. The site of the disease and the histology were also recorded in addition to the various sociodemographic parameters.

RESULTS

Out of 55,742 patients registered in our hospital; 3,667 were diagnosed to have EC. Male:female ratio was 1.15:1. The mean age was 54.6 ± 11.74 years; 66.15% of the patients were illiterate and 48.6% belonged to the low socioeconomic status. Smoking and alcohol consumption were identified as risk factors in 48 and 25.6% of the patients, respectively.

CONCLUSIONS

The etiology in majority of the patients is linked to tobacco and alcohol, thus, modification of life style with limiting the use of addictions may be an effective strategy in the prevention of this dreaded and mostly incurable disease.

摘要

背景

尽管食管癌(EC)治疗方面取得了各种进展,但作为对癌症治疗反应最差的肿瘤之一,其总体预后仍然很差。因此,了解与食管癌相关的各种社会人口学因素,以找出该疾病的一级预防方案具有重要意义。

材料与方法

这是一项对2003年1月至2012年12月在印度西北部地区癌症中心登记的食管癌患者病历的回顾性分析。除了各种社会人口学参数外,还记录了疾病部位和组织学情况。

结果

在我院登记的55742例患者中,3667例被诊断为食管癌。男女比例为1.15:1。平均年龄为54.6±11.74岁;66.15%的患者为文盲,48.6%属于社会经济地位较低者。吸烟和饮酒分别被确定为48%和25.6%患者的危险因素。

结论

大多数患者的病因与烟草和酒精有关,因此,通过改变生活方式限制成瘾物质的使用可能是预防这种可怕且大多无法治愈疾病的有效策略。

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Light alcohol drinking and cancer: a meta-analysis.轻至中度饮酒与癌症:荟萃分析。
Ann Oncol. 2013 Feb;24(2):301-308. doi: 10.1093/annonc/mds337. Epub 2012 Aug 21.
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Cancer statistics, 2012.癌症统计数据,2012 年。
CA Cancer J Clin. 2012 Jan-Feb;62(1):10-29. doi: 10.3322/caac.20138. Epub 2012 Jan 4.

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